Preparation and optimization of a drug delivery system based on berberine chloride-immobilized MgAl hydrotalcite

Djebbi, Mohamed Amine; Bouaziz, Zaineb; Elabed, Alae; Sadiki, Moulay; Abed, Soumya El; Namour, Philippe; Jaffrézic‐Renault, Nicole; Amara, Abdesslem Ben Haj

doi:10.1016/j.ijpharm.2016.04.048

Cited by 30 publications

(14 citation statements)

References 57 publications

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“…The berberine chloride (BBC), known as an antibacterial agent, was intercalated in both Mg 2 Al and Zn 2 Al . While LDH itself does not display any antibiotic activity, hybrid LDH‐BBC materials display strong inhibition against growth of S. aureus , P. aeruginosa and B. subtilus , known to cause human infections.…”

Section: Ldh and Biological Cell Interactionssupporting

confidence: 76%

Interactions between Biological Cells and Layered Double Hydroxides: Towards Functional Materials

Forano

Bruna

Mousty

et al. 2018

The Chemical Record

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This review highlights the current research on the interactions between biological cells and Layered Double Hydroxides (LDH). The as-prepared biohybrid materials appear extremely attractive in diverse fields of application relating to health care, environment and energy production. We describe how thanks to the main features of biological cells and LDH layers, various strategies of assemblies can be carried out for constructing smart biofunctional materials. The interactions between the two components are described with a peculiar attention to the adsorption, biocompatibilization, LDH layer internalization, antifouling and antimicrobial properties. The most significant achievements including authors' results, involving biological cells and LDH assemblies in waste water treatment, bioremediation and bioenergy generation are specifically addressed.

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Section: Ldh and Biological Cell Interactionssupporting

confidence: 76%

Interactions between Biological Cells and Layered Double Hydroxides: Towards Functional Materials

Forano

Bruna

Mousty

et al. 2018

The Chemical Record

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“…NiAl LDH intercalated with NO 3 − was prepared using the co‐precipitation method previously reported in our published works . Typically, 50 mL of a 1.0 M metallic solution containing 9.03 mg of NiCl 2 ⋅ 6H 2 O and 3.98 mg of AlCl 3 ⋅ 6H 2 O with a molar ratio Ni(II)/Al(III) of 2 was added dropwise into a reactor containing a solution of 0.5 M NaNO 3 (100 mL) under vigorous stirring at room temperature and nitrogen gas flow.…”

Section: Methodsmentioning

confidence: 80%

Chlorpromazine Electro‐oxidation at BDD Electrode Modified with nZVI Nanoparticles Impregnated NiAl LDH

et al. 2020

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Nanocomposite of nanoscale zero‐valent iron (nZVI) and layered double hydroxide (LDH) was used as modifier for boron‐doped diamond electrode in determination of anti‐psychotic drug chlorpromazine (CPZ). nZVI nanoparticles were prepared by liquid phase reduction of ferric chloride with sodium borohydride on the surface of NiAl LDH matrix owing to the strong exchange and confinement efficiency of LDH. The structure, binding and surface properties of the nZVI@LDH nanocomposite were monitored using powder X‐ray diffractometry, FT‐IR spectroscopy, scanning and transmission microscopy and BET techniques. The electrochemical properties of the modified electrode were investigated by CV and EIS, performed in a phosphate buffer containing ferro/ferricyanide as redox probe. The modified electrode exhibited excellent electrochemical performance compared with unmodified electrode. As regard potential application of the nanocomposite surface to the CPZ detection, square‐wave voltammetric signals showed a good linear correlation over CPZ concentrations in a broad range from 0.1 to 8.0 μM with low detection limit of 0.005 μM. Nevertheless, these results suggest that the proposed nanocomposite modifier surface provides exceptional synergy and significant enhancement effect to the voltammetric response of CPZ and thus could be applied as highly efficient and stable platform of sensors in clinical analysis.

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“…Combined with Gentamicin (GE), a bactericide agent, g‐POEGMA‐GE was grafted onto CaAl LDH using RAFT polymerization followed by an esterification reaction. [283b] The g‐POEGMA‐GE/CaAl LDH displays antibiotic activity against Gram‐positive S. aureus . Moreover, the functionalization of LDH platelets with some polymers allows the immobilization of metal nanoparticles with antibacterial properties, such as AgNP that have demonstrated high biocide efficiency.…”

Section: Ldh Bio‐nanocompositesmentioning

confidence: 99%

Tailoring Hybrid Layered Double Hydroxides for the Development of Innovative Applications

Taviot-Guého

Prévot

Forano

et al. 2017

Adv Funct Materials

240

142

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International audienceHybrid materials based on layered double hydroxides (LDHs) exhibit great potential in diverse fields such as health care, polymer composites, environment, catalysis, and energy generation. Indeed, the compositional flexibility and the scalability of LDH structures, their low cost, and their ease of synthesis have made hybrid LDHs extremely attractive for constructing smart and high-performance multifunctional materials. This review provides a comprehensive and critical overview of the current research on multifunctional hybrid LDHs. Organic–inorganic hybrid LDHs, intercalated and surface-immobilized structures, are both specifically addressed. The new trends and strategies for hybrid LDH synthesis are first described, and then the potential of the latest hybrid LDHs, polymer LDH nanocomposites, and LDH bio-nanocomposites are presented. Significant achievements published from ≈2010, including authors' results, which employ hybrid LDH assemblies in materials science, medicine, polymer nanocomposites, cement chemistry, and environmental technologies, are specifically addressed. It is concluded with remarks on present challenges and future prospects

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Preparation and optimization of a drug delivery system based on berberine chloride-immobilized MgAl hydrotalcite

Cited by 30 publications

References 57 publications

Interactions between Biological Cells and Layered Double Hydroxides: Towards Functional Materials

Interactions between Biological Cells and Layered Double Hydroxides: Towards Functional Materials

Chlorpromazine Electro‐oxidation at BDD Electrode Modified with nZVI Nanoparticles Impregnated NiAl LDH

Tailoring Hybrid Layered Double Hydroxides for the Development of Innovative Applications

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