Preparation and some Physical Characterization of Rice Starch - Carboxymethyl Cellulose as Hemostatic Film

Abstract

Rice starch (RS) and carboxymethyl cellulose (CMC) are natural polymers that can be widely used for numerous biomedical applications such as hydrogels, capsules, drug delivery system, wound dressing. The purpose of this study was to prepare and investigate the appropriate weight ratio of RS/CMC blend films by solution casting technique. The swelling ratio and solubility were evaluated. The mechanical properties, intermolecular interaction, and morphology were also analyzed by the universal mechanical testing, Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM), respectively. The results indicated that the suitable ratio of RS/CMC blend film was 60/40. The swelling ratio, solubility, tensile strength, and elongation at break were 46.8±0.3 times, 21.63±0.72 %, 30.4±1.5 MPa and 5.76±0.31 %, respectively. Moreover, the physical linkages exhibited mainly between the hydroxyl groups of RS and the carboxyl groups of CMC. In addition, the cross-sectional SEM images of blended films showed the miscibility of RS and CMC. This study suggested that the RS/CMC blended film can be used as a hemostatic film.

Mechanical and Physicochemical Properties of Composite Biopolymer Films Based on Carboxymethyl Cellulose from Young Palmyra Palm Fruit Husk and Rice Flour

“…According to these findings, these peaks were minimally shifted to different higher wavenumbers when the levels of RF increased, and were mostly related to the properties of films changing. Similar results have been found in CMC from durian rind/rice starch composite films [6], fish gelatin/rice flour blended films [12], CMC/alginate/chitosan [15], rice starch/CMC blended films [17], and also CMC/cassava starch blended films [22]. The shift in the wavenumbers of the films demonstrates the interactions between the carboxyl groups of CMCy and the hydroxyl groups of RF.…”

“…The FTIR spectrum of the CMCy film displayed major bands at 3274.17, 2874.50, 1589.37, and 1413.49 cm −1 , referring to the -OH groups stretching, the C-H stretching vibration, antisymmetric stretching vibration of COO-groups, and symmetric stretching vibration of COO-groups, respectively [27]. The bands at 996.09 and 895.82 cm −1 are assigned to the -CH ring and C-C stretching vibrations, respectively [17] (Figure 5A).…”

“…The combinations of biopolymer materials to produce composite films with the aim of improving the properties of the resulting composite films have been investigated. Some include CMC/alginate/chitosan [15], cassava starch/CMC [16], rice starch/CMC [17], starch/CMC [18], potato starch/CMC [19], corn and cassava starch/CMC [20], and CMC/ chitosan [21]. The mechanical, physicochemical, thermal, and/or gas/moisture barrier properties of the resulting composite biopolymer films might be enhanced based on component interactions within the film structures [22].…”

Effects of Algan hemostatic agent foam in rat femoral artery injury model: A randomized animal trial

“…Recently, the hemostatic effects of AHA foam have been reported [10][11][12]. In addition, the effectiveness and safety of the different forms of AHA have been studied [13][14][15][16].…”