Preparation and validation of [67Ga]Ga-phytate kit and Monte Carlo dosimetry: an effort toward developing an impressive lymphoscintigraphy tracer

Bayat, Zeinab; Saeedzadeh, Elham; Vahidfar, Nasim; Sadeghi, Mahdi; Farzenefar, Saeed; Daha, Fariba Johari; Salehi, Yalda

doi:10.1007/s10967-021-08183-z

Cited by 6 publications

(1 citation statement)

References 25 publications

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“…Finally, 99m Tc-labeled colloids have been considered for detection of sentinel node (SLN) using planar scintigraphy and, more recently, SPECT or SPECT/CT [ 98 , 99 , 100 , 101 ]. There is evidence from studies in vulvar cancer patients that indocyanine green (ICG)-[ 99m Tc]Tc-nanocolloid SPECT/CT can be used for personalized lymphatic mapping, possibly providing detailed information about the number and the anatomical location of SNs for adequate surgical guidance [ 98 , 102 , 103 ].…”

Section: Vulvar Cancermentioning

confidence: 99%

A Review of Nuclear Medicine Approaches in the Diagnosis and the Treatment of Gynecological Malignancies

Vahidfar

Farzanefar

Ahmadzadehfar

et al. 2022

Cancers

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Nuclear medicine is defined as the diagnosis and the treatment of disease using radiolabeled compounds known as radiopharmaceuticals. Single-photon emission computed tomography/computed tomography (SPECT/CT) and positron emission tomography/computer tomography (PET/CT) based radiopharmaceuticals have proven reliable in diagnostic imaging in nuclear medicine and cancer treatment. One of the most critical cancers that also relies on an early diagnosis is gynecological cancer. Given that approximately 25% of all cancers in developing countries are a subset of gynecological cancer, investigating this cancer subtype is of significant clinical worth, particularly in light of its high rate of mortality. With accurate identification of high grade distant abdominal endometrial cancer as well as extra abdominal metastases, 18F-Fluorodeoxyglucose ([18F]FDG) PET/CT imaging is considered a valuable step forward in the investigation of gynecological cancer. Considering these factors, [18F]FDG PET/CT imaging can assist in making management of patient therapy more feasible. In this literature review, we will provide a short overview of the role of nuclear medicine in the diagnosis of obstetric and gynecological cancers.

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