Preparation, characterization, and biological activity of Cinnamomum cassia essential oil nano-emulsion

Liang, Dongyi; Feng, Baijian; Li, Na; Su, Linhan; Wang, Zhong; Kong, Fanrong; Bi, Yutie

doi:10.1016/j.ultsonch.2022.106009

Cited by 47 publications

(20 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The assurance of antimicrobial quality in cosmetics is normally approached by the addition of preservatives that maintain their microbiological purity during manufacture, packing, storage, but especially during the entire period of usage [ 35 ].However, preservatives are considered as one of the main factors inducing allergies to users [ 36 ].To overcome these drawbacks, numerous approaches have been focused on the discovery of potent bioavailable and biocompatible ingredients with antimicrobial properties, such as polymer agents, chitosan [ 1 ]; herbal extracts, aloe vera [ 37 ] and calendula [ 48 ]; and essential oils, Lavandulla [ 49 ] and cinnamomum [ 50 ].…”

Section: Resultsmentioning

confidence: 99%

Formulation, Characterization and Evaluation of Innovative O/W Emulsions Containing Curcumin Derivatives with Enhanced Antioxidant Properties

et al. 2022

View full text Add to dashboard Cite

In the present study, a series of semisolid Oil in Water (O/W) emulsions containing different Curcumin (Cur) derivatives (Cur powder, Cur extract and Cur complexed with β-cyclodextrin) in varying concentrations, were prepared. Initially, Dynamic Light Scattering (DLS), microscopy, pH and viscosity measurements were performed to evaluate their stability over time. Moreover, the effect of the active cosmetic substances on the Sun Protection Factor (SPF), antimicrobial and antioxidant properties of the prepared emulsions was investigated. It was observed that emulsions containing Cur extract and Cur β-cyclodextrin complex presented great viscosity and pH stability for up to 90 days of storage contrary to the emulsions containing Cur powder which showed unstable behavior due to the formation of agglomerates. All samples presented SPF values between 2.6 and 3.2. The emulsions with Cur in all forms exhibited high antioxidant activity, whereas the emulsion containing Cur β-cyclodextrin complex presented the highest value. Despite their improved stability and antioxidant activity, the emulsions containing Cur extract and Cur-β-cyclodextrin exhibited a low percentage of antimicrobial activity against E. coli and Staphylococcus bacteria. Instead, the emulsions containing Cur powder presented a reduction rate over 90 % against E. coli and Staphylococcus colonies.

show abstract

Section: Resultsmentioning

confidence: 99%

Formulation, Characterization and Evaluation of Innovative O/W Emulsions Containing Curcumin Derivatives with Enhanced Antioxidant Properties

et al. 2022

View full text Add to dashboard Cite

show abstract

“…However, the essential oil has been severely restricted because it is hardly soluble in water. Increasing the solubility of the essential oil can be accomplished by using an oil-in-water emulsion, which is an appropriate approach [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

“…Unfortunately, due to their poor solubility in water, the effectiveness of essential oil therapy has been severely limited [ 13 ]. Apart from this, there are still some limitations, including the fact that CEO is generally sensitive to external factors such as temperature, light, and oxygen.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Antioxidant, Antibacterial, and Anticancer Activity of Ultrasonic Nanoemulsion of Cinnamomum Cassia L. Essential Oil

Alam

Ansari

Alqarni

et al. 2023

Plants

View full text Add to dashboard Cite

Cinnamomum cassia (C. assia) has long been used in traditional holistic medicine for its medicinal properties. It is used as an antioxidant, antibacterial, anti-inflammatory and anticancer agent. Cinnamon, in particular, the essential oil of C. cassia, has significant biological properties. Despite this, the volatility, stability, and insolubility of C. cassia essential oil (CEO) remain the main disadvantages that limit its application, ultimately affecting its pharmacological efficacy. To find a solution to this problem, we developed the CEO nanoemulsion (CEO-NE). For lipophilic compounds, insoluble nanoemulsion-based formulations are a popular delivery strategy. In this research work, a highly stable dosage form named CEO-NE was successfully developed using polysorbate 80 and water. The findings show that the synthesized CEO has a uniform shape with a PDI of 0.380 and an adequate particle size of 221.8 nm. The antioxidant outcomes show excellent results for CEO-NE compared to CEO against DPPH and hydrogen peroxide. The obtained antibacterial activity of CEO-NE was more efficient than that of CEO against Klebsiella pneumonia (MTCC 8911) with 0.025% and 0.05%, respectively. The CEO-NE preparation was tested against an alveolar lung adenocarcinoma cell line (A549) with an IC50 of 50.21 µg/mL for CEO and 18.05 µg/mL for CEO-NE, respectively. These results are encouraging for future translational studies on CEO-NE use in lung cancer therapy due to its excellent antioxidant, antibacterial, and killing kinetic properties.

show abstract

“…These bioactive compounds are reported to have displayed substantial antimicrobial activity against a wide range of microbes including E. coli, S. enterica and S. aureus (da Silva Barbosa et al ., 2021). Additionally, CEO has also displayed considerable anti‐oxidant, anti‐tumour, anti‐diabetic and anti‐inflammatory activities (Liang et al ., 2022).…”

Section: Introductionmentioning

confidence: 99%

Development, characterization, and assessment of antioxidant pectin–sodium alginate based edible films incorporated with cassia essential oil

Bhatia

Al‐Harrasi

Jawad

et al. 2023

Int J of Food Sci Tech

View full text Add to dashboard Cite

SummaryThis research was conducted in order to develop a sustainable and eco‐friendly pectin–sodium alginate‐based packaging material using natural additives. Cassia essential oil (CEO) is a GRAS‐approved natural preservative and flavouring agent used for a variety of food products. Recent reports revealed the growing interest in using oils in packaging material as natural additives. In the current study, CEO is loaded in pectin–sodium alginate‐based composite films. The main component observed in CEO was cinnamaldehyde which was evaluated by employing gas chromatography–mass spectrometry (GCMS) analysis. Moreover, the incorporation of CEO improved the tensile strength (TS) and elongation at break (EAB) and increased the opacity of the films. However, a decrease in the moisture content, water solubility and water vapour permeability was observed with the incorporation of EO. Additionally, SEM analysis of the CEO‐loaded films revealed an improvement in their morphology. The results of the DPPH and ABTS cation scavenging assays revealed a significant (P ≤ 0.05) increase in antioxidant activity with the incorporation of CEO. These findings indicate that cassia essential oil can be employed as a natural additive to develop edible active packaging material.

show abstract

Preparation, characterization, and biological activity of Cinnamomum cassia essential oil nano-emulsion

Cited by 47 publications

References 39 publications

Formulation, Characterization and Evaluation of Innovative O/W Emulsions Containing Curcumin Derivatives with Enhanced Antioxidant Properties

Formulation, Characterization and Evaluation of Innovative O/W Emulsions Containing Curcumin Derivatives with Enhanced Antioxidant Properties

Antioxidant, Antibacterial, and Anticancer Activity of Ultrasonic Nanoemulsion of Cinnamomum Cassia L. Essential Oil

Development, characterization, and assessment of antioxidant pectin–sodium alginate based edible films incorporated with cassia essential oil

Contact Info

Product

Resources

About