2022
DOI: 10.3390/bios12121139
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Preparation of a Highly Sensitive Electrochemical Aptasensor for Measuring Epirubicin Based on a Gold Electrode Boosted with Carbon Nano-Onions and MB

Abstract: Epirubicin is prescribed as an essential drug for treating breast, prostate, uterine, and gastrointestinal cancers. It has many side effects, such as heart failure, mouth inflammation, abdominal pain, fever, and shortness of breath. Its measurement is necessary by straightforward and cheap methods. The application of aptamer-based electrochemical sensors is accounted as a selective option for measuring different compounds. In this work, a thiol-modified aptamer was self-assembled on the surface of the gold ele… Show more

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Cited by 22 publications
(1 citation statement)
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“…Many of the previous works paid attention to chemically modified electrodes, where the bound species are usually electrochemically active molecules 22 . When such modified electrodes are used as sensors in electroanalytical applications, they can be expected to be involved in charge transfer between the modifier on the electrode surface and the compound in the solution, leading to an increase in the response and a change in the reaction potential 26 30 .…”
Section: Introductionmentioning
confidence: 99%
“…Many of the previous works paid attention to chemically modified electrodes, where the bound species are usually electrochemically active molecules 22 . When such modified electrodes are used as sensors in electroanalytical applications, they can be expected to be involved in charge transfer between the modifier on the electrode surface and the compound in the solution, leading to an increase in the response and a change in the reaction potential 26 30 .…”
Section: Introductionmentioning
confidence: 99%