Preparation of a restricted access material–macroporous hybrid monolithic column – for on-line solid-phase extraction of the sulfonamides residues from honey

Abstract

A novel RAM–HMC with superior enrichment and clean-up efficiency was prepared by an in situ method in a stainless-steel column, and used as a pre-column for on-line solid-phase extraction of sulfonamides residues from honey.

Preparation of restricted‐access material precolumns by grafting δ‐gluconolactone onto a hybrid silica monolithic column for on‐line solid‐phase extraction of tetracycline residues from milk

“…Initially, the RAM‐HMC was prepared according to our previous work . The results of this research found that single organosilane (MTMS) was significantly different from mixed silanes (MTMS and tetramethoxysilane).…”

“…The column has low column pressure and high mass transfer efficiency owing to unique pore structure . With the advantages of facile preparation, abundant surface functional groups, and controlled pore sizes distribution, the monolithic columns have been numerous reports such as organic polymer‐based, silica‐based and organic‐silica hybrid monolithic columns . Compard to the former monoliths, the hybrid monolithic column combines the merits of the former two monoliths and overcomes the inherent drawbacks like the instability under extreme pH and harsh solvents .…”

“…With the advantages of facile preparation, abundant surface functional groups, and controlled pore sizes distribution, the monolithic columns have been numerous reports such as organic polymer‐based, silica‐based and organic‐silica hybrid monolithic columns . Compard to the former monoliths, the hybrid monolithic column combines the merits of the former two monoliths and overcomes the inherent drawbacks like the instability under extreme pH and harsh solvents . Therefore, combining the advantages of both, the hybrid monolithic column (HMC) can be modified to prepare a novel adsorbent (RAM‐HMC) for on‐line clean‐up and enrichment of veterinary drug residues in foods.…”

Poly[(2‐(acryloyloxy) ethyl]trimethylammonium chloride‐co‐ethylene dimethacrylate monolith on‐line solid‐phase extraction coupled with liquid chromatography and tandem mass spectrometry for the fast determination of salicylic acid in foodstuffs

“…Moreover, polymeric monolithic columns with different polarities and functional groups can be fabricated by varying their chemical composition and configuration according to the analysis requirements. Because of these advantages, several polymer-based monolithic columns have been successfully used for the on-line pretreatment of compounds from environmental, food, and biological matrixes [21][22][23][24][25][26][27][28][29][30][31], e.g., ion-exchange sorbents [22], reversed-phase monoliths [24], restricted access monoliths [26], molecularly imprinted polymers [27], and hydrophilic sorbents [30]. The polyfunctional monolith monomers will dictate the extraction performance of the target analytes.…”

A novelty strategy for the fast analysis of sulfonamide antibiotics in fish tissue using magnetic separation with high‐performance liquid chromatography–tandem mass spectrometry

“…In order to achieve the determination of trace SAs, various sample preparation methods have been developed in various matrices, such as QuEChERS (quick, easy, cheap, effective, rugged and safe) method in animal tissues combined with highperformance liquid chromatography-Orbitrap (HPLC-Orbitrap) (Abdallah et al, 2014), solid-phase extraction method in water sample combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS) (Zhou et al, 2012), microwave-assisted extraction method in sediments and soils combined with LC-MS/MS (Balakrishnanvimal et al, 2014) and on-line solid-phase extraction in honey combined with LC-MS/MS (Lv et al, 2015). However, these protocols usually need multi-step processing and have been proven to be time-consuming.…”