Preparation of core–shell structural surface molecular imprinting microspheres and recognition of l-Asparagine based on [N1111]Asn ionic liquid as template

Ji, Li; Hu, Xiaoling; Guan, Ping; Song, Renyuan; Zhang, Xiangrong; Tang, Yimei; Wang, Chaoli; Qian, Liwei

doi:10.1016/j.reactfunctpolym.2015.01.002

Cited by 6 publications

(4 citation statements)

References 31 publications

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“…Since the nineties, the number of publications in this area increased exponentially [ 58 ] with applications in many different fields, including the production of MIPs, wherein ILs started to be used as solvents [ 59 , 60 , 61 , 62 , 63 , 64 , 65 ], and further with other functionalities, such as templates ( Figure 2 ) [ 66 , 67 , 68 , 69 ], monomers [ 70 , 71 , 72 ], crosslinkers [ 73 ] or additives to polymer reactions.…”

Section: Green Strategies In Mip Developmentmentioning

confidence: 99%

Green Strategies for Molecularly Imprinted Polymer Development

2018

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Molecular imprinting is a powerful technology to create artificial receptors within polymeric matrices. Although it was reported for the first time by Polyakov, eighty-four years ago, it remains, nowadays, a very challenging research area. Molecularly imprinted polymers (MIPs) have been successfully used in several applications where selective binding is a requirement, such as immunoassays, affinity separation, sensors, and catalysis. Conventional methods used on MIP production still use large amounts of organic solvents which, allied with stricter legislation on the use and release of chemicals to the environment and the presence of impurities on final materials, will boost, in our opinion, the use of new cleaner synthetic strategies, in particular, with the application of the principles of green chemistry and engineering. Supercritical carbon dioxide, microwave, ionic liquids, and ultrasound technology are some of the green strategies which have already been applied in MIP production. These strategies can improve MIP properties, such as controlled morphology, homogeneity of the binding sites, and the absence of organic solvents. This review intends to give examples reported in literature on green approaches to MIP development, from nano-to micron-scale applications.

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Section: Green Strategies In Mip Developmentmentioning

confidence: 99%

Green Strategies for Molecularly Imprinted Polymer Development

2018

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“…The monodispersed polymeric beads were also widely used for grafting MIP layers because of their characteristic large surface area to volume ratio and the promising surface properties for immobilizing CRP initiators. These polymeric supports include poly(GMA), poly(EGDMA- co -MAA), poly(DVB), poly[EGDMA- co -4-vinylpyridine (4-VP)] and polyethyleneterephthalate (PET). , Zhao and co-workers prepared the macroporous core–shell MIP particles for selective recognition of 2,4-dichlorophenoxyacetic acid (2,4-D), which has been used as herbicide and has shown potential damage to the vital organs of human (such as kidney and liver) . The monodispersed macroporous poly(GMA) particles were synthesized and used as supporting matrix for preparing surface MIP particles (PGMA@MIP).…”

Section: Molecularly Imprinted Polymers (Mips)mentioning

confidence: 99%

Functional Interfaces Constructed by Controlled/Living Radical Polymerization for Analytical Chemistry

Wang

Song

Hang

2016

ACS Appl. Mater. Interfaces

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The high-value applications of functional polymers in analytical science generally require well-defined interfaces, including precisely synthesized molecular architectures and compositions. Controlled/living radical polymerization (CRP) has been developed as a versatile and powerful tool for the preparation of polymers with narrow molecular weight distributions and predetermined molecular weights. Among the CRP system, atom transfer radical polymerization (ATRP) and reversible addition-fragmentation chain transfer (RAFT) are well-used to develop new materials for analytical science, such as surface-modified core-shell particles, monoliths, MIP micro- or nanospheres, fluorescent nanoparticles, and multifunctional materials. In this review, we summarize the emerging functional interfaces constructed by RAFT and ATRP for applications in analytical science. Various polymers with precisely controlled architectures including homopolymers, block copolymers, molecular imprinted copolymers, and grafted copolymers were synthesized by CRP methods for molecular separation, retention, or sensing. We expect that the CRP methods will become the most popular technique for preparing functional polymers that can be broadly applied in analytical chemistry.

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“…Compared with the SEM images of surface-CTA, the surfaces of MIPs1 (b), MIPs2 (c) and NIPs (d) are rough, proving that the NIPs/MIPs with new polymer film. 39 This might be caused by the physical and chemical properties of IL. To verify the chemical structure, the FT-IR was used, and the results are shown are also observed in the spectra, it indicated that MIPs and NIPs coatings were successfully prepared.…”

Section: Morphological Characterizationmentioning

confidence: 99%

“…The morphologies are similar to the core-shell Asn-MIP structure which was described in our previously reported work. 39 This might be caused by the physical and chemical properties of ILs. An IL is a kind of organic salt which consists of only ions.…”

Section: Morphological Characterizationmentioning

confidence: 99%

Preparation of molecularly imprinted polymers using ion-pair dummy template imprinting and polymerizable ionic liquids

Guan

et al. 2015

RSC Adv.

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a Ionic liquid based molecularly imprinted polymers have attracted considerable attention as a biomimetic recognition materials due to water-compatibility and high binding capacity. However, the selective recognition was unsatisfactory. In order to overcome this defect, we developed a novel dummy template ionic liquid based molecularly imprinted polymer, which use 1-butyl-3-vinylimidazolium α-aminohydrocinnamic acid salt as a functional monomer and dummy template. The binding experiment show that the obtained molecularly imprinted polymer possess high bind capacity (280.18 μmol·g -1 ), imprinting factor (3.17) and selective factor (5.75). The molecular simulation results demonstrated that the high selectivity is attributed to forming the ion-pairs between imidazolium and L-phenylalanine, which might be located in imprinted cavities to improve imprinted efficiency. Subsequently, the dummy template ionic liquid based imprinted polymer was employed as solid phase extraction packings to analyze the L-phenylalanine from the blood of phenylketonuria patient. The results indicated that the obtained dummy template ionic liquid based imprinted polymer has a good analytical performance. Thus, the dummy imprinting combined with ionic liquid is a useful way to improve the specific recognition of ionic liquid based molecular imprinted polymers, so that this method offers promising new applications in the field of analysis of biologic samples.

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Preparation of core–shell structural surface molecular imprinting microspheres and recognition of l-Asparagine based on [N1111]Asn ionic liquid as template

Cited by 6 publications

References 31 publications

Green Strategies for Molecularly Imprinted Polymer Development

Green Strategies for Molecularly Imprinted Polymer Development

Functional Interfaces Constructed by Controlled/Living Radical Polymerization for Analytical Chemistry

Preparation of molecularly imprinted polymers using ion-pair dummy template imprinting and polymerizable ionic liquids

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