Prepubertal Anorexia Nervosa and Major Depressive Disorder

Alessi, Norman E.; Krahn, Dean D.; Brehm, Donna; Wittekindt, John

doi:10.1097/00004583-198905000-00013

Cited by 15 publications

(9 citation statements)

References 32 publications

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“…Anorexia nervosa Fifteen studies reported on inpatient treatment utilizing a behaviour therapy approach (4 case series and 11 case reports ) [214][215][216][217][218][219][220][221][222][223][224][225][226][227][228] ( Table 43). These studies included a total of 219 patients.…”

Section: Behaviour Therapy Based Inpatient Carementioning

confidence: 99%

“…Two studies reported on EAT scores over the course of inpatient treatment. One was a case report describing that EAT scores remained high for the first 7 weeks of treatment and then dropped (from total score of 60 to 10) over the last 3 weeks of a 10-week admission [225]. The other study measured EAT scores in 24 patients at admission and discharge (mean length of stay 11 weeks) and reported a change from total mean EAT of 37.1 at admission to 12.7 at discharge (p = 0.0001) [224].…”

Section: Behaviour Therapy Based Inpatient Carementioning

confidence: 99%

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Canadian practice guidelines for the treatment of children and adolescents with eating disorders

et al. 2020

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Objectives: Eating disorders are common and serious conditions affecting up to 4% of the population. The mortality rate is high. Despite the seriousness and prevalence of eating disorders in children and adolescents, no Canadian practice guidelines exist to facilitate treatment decisions. This leaves clinicians without any guidance as to which treatment they should use. Our objective was to produce such a guideline. Methods: Using systematic review, the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system, and the assembly of a panel of diverse stakeholders from across the country, we developed high quality treatment guidelines that are focused on interventions for children and adolescents with eating disorders. Results: Strong recommendations were supported specifically in favour of Family-Based Treatment, and more generally in terms of least intensive treatment environment. Weak recommendations in favour of Multi-Family Therapy, Cognitive Behavioural Therapy, Adolescent Focused Psychotherapy, adjunctive Yoga and atypical antipsychotics were confirmed. Conclusions: Several gaps for future work were identified including enhanced research efforts on new primary and adjunctive treatments in order to address severe eating disorders and complex co-morbidities.

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Section: Behaviour Therapy Based Inpatient Carementioning

confidence: 99%

Section: Behaviour Therapy Based Inpatient Carementioning

confidence: 99%

Canadian practice guidelines for the treatment of children and adolescents with eating disorders

et al. 2020

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“…Mainly teenage girls and young women between 15 and 24 years of age are affected. Five percent of AN patients are reported to be less than 12 years of age ( 2). This so‐called early onset form is thought to be on the increase.…”

Section: Diagnostic Criteria For Anorexia and Bulimia Nervosa (1)mentioning

confidence: 99%

Dermatologic Findings in Anorexia and Bulimia Nervosa of Childhood and Adolescence

Schulze

Pettke-Rank

Kreienkamp

et al. 1999

Pediatric Dermatology

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The cutaneous signs of anorexia nervosa (AN) and bulimia nervosa (BN) have been described previously in adult patients. For the first time, we present here dermatologic findings in children and adolescents suffering from eating disorders. Thirty consecutive young anorexic and bulimic inpatients (8 to 17 years of age, mean 15.1 years) underwent a standardized dermatologic examination. Patients were checked for abnormalities of the skin including atopic stigmata, dermographism, hair, nails, and oral cavity. Serum was obtained for hemoglobin, iron, zinc, GPT, thyroid, and sex-hormone levels. In 13 patients, the total serum IgE was determined, and a prick test was carried out with defined type I allergens. Findings in order of frequency included xerosis of the skin, white dermographism, diffuse hypertrichosis, acrocyanosis, scars, diffuse effluvium, artifacts, brittle nails, and onychophagia. Significant co-relations were found between the presence of hypertrichosis and the existence of amenorrhea or a body mass index of less than 16. In 22 patients a low T3 level was found. In summary, children and adolescents suffering from AN or BN show dermatologic features similar to those reported in older patients. Special findings in this age group are extensive lanugo hair and signs of autoaggressive behavior.

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“…Fourteen additional studies reported on a behaviour therapy approach (total n = 218) [44][45][46][47][48][49][50][51][52][53][54][55][56][57]. Various approaches to reporting change in weight were used, and all studies reported a positive change in weight from admission to discharge (Table 1).…”

Section: Resultsmentioning

confidence: 99%

“…Cinciripini et al (1983) described a case report in which purging after meals decreased from 48% of meals/week to 0% of meals per week [47]. Two other studies reported on EAT scores, both of which showed a reduction in scores during admission [44,57]. Of note, Alessi et al (1989) reported that EAT scores remained high for the first 7 weeks of treatment (with weight gain of 4.5 kg over the first 7 weeks) and scores then dropped (from total score of 60 to 10) during the last 3 weeks of a 10week admission.…”

Section: Symptom Changementioning

confidence: 99%

Outcomes of inpatient psychological treatments for children and adolescents with eating disorders at time of discharge: a systematic review

et al. 2020

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Background: Recommended first line treatment for children and adolescent eating disorders is outpatient therapy. However, a significant number of children and adolescents with eating disorders continue to require inpatient treatment during the course of their illness. The effect of psychological treatments in an inpatient setting on outcomes at the time of discharge remains unclear. This paper presents the results of a review of the literature on outcomes at the time of discharge following inpatient psychological treatment for children and adolescents with eating disorders. Main body: The majority of studies found were observational and of low quality. The most consistently reported positive outcome of inpatient treatment is weight gain. Results related to symptom change and motivation vary between studies. Within the inpatient setting, there is considerable heterogeneity in the types of treatments offered, goals of treatment, length of stay and outcomes measured. Conclusion: There remains a paucity of high-quality studies examining the effect of psychological treatments provided to children and adolescents in an inpatient setting. The significant heterogeneity between studies makes it not possible to compare across studies. Future research should aim to resolve these deficiencies in order to better determine the specific factors that contribute to positive outcomes of inpatient treatment for children and adolescents with eating disorders.

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Prepubertal Anorexia Nervosa and Major Depressive Disorder

Cited by 15 publications

References 32 publications

Canadian practice guidelines for the treatment of children and adolescents with eating disorders

Canadian practice guidelines for the treatment of children and adolescents with eating disorders

Dermatologic Findings in Anorexia and Bulimia Nervosa of Childhood and Adolescence

Outcomes of inpatient psychological treatments for children and adolescents with eating disorders at time of discharge: a systematic review

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