Prescribing pattern of psychotropic drugs used in non-psychiatric patients among outpatient department of two teaching hospitals in Bangladesh

Alam, Nazmun Nahar; Ara, Ferdous; Iqbal, Md. Jalal Uddin

doi:10.3329/bjp.v10i1.21463

Cited by 2 publications

(4 citation statements)

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“…In our study, the majority of patients were prescribed SGAs. These results are consistent with the results from similar studies conducted in Australia, Bahrain, Germany, and the United States, where most schizophrenic patients were treated with SGAs [7,10,11,19,20].…”

Section: Discussionsupporting

confidence: 91%

Antipsychotic prescription patterns and treatment costs of schizophrenia in northwestern Pakistan: A one-year observational study

Khan¹,

Iqbal²,

Sultan³

et al. 2018

Trop. J. Pharm Res

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Purpose: To evaluate the antipsychotic drugs most commonly prescribed for schizophrenia patients in Peshawar, Pakistan and to analyze the treatment costs associated with these drugs. Methods: One hundred patients diagnosed with schizophrenia were recruited from outpatient psychiatry departments in Peshawar, Pakistan and followed for one year. Demographic data were collected for each patient at the beginning of the study. A questionnaire was used to collect antipsychotic prescription information at 4, 8 and 12 months. The cost of antipsychotics was obtained from PharmaGuide, Pakistan. The cost associated with antipsychotic drug use was statistically analyzed using post hoc tests. Results: Of the patients who completed this study, 68.1 % were prescribed second-generation antipsychotic (SGA) drugs, 6.9 % first-generation antipsychotic (FGA) drugs, and 25.0 % a combination of SGAs and FGAs. Furthermore, 40.3 % of the patients who completed the study received antipsychotic monotherapy and 34.7 % antipsychotic polytherapy. In monotherapy, risperidone was the most commonly prescribed antipsychotic drug, used by 44.8 % of patients while in polytherapy, risperidone plus olanzapine was the most commonly prescribed combination, used by 32 % of patients. Switching of antipsychotic drugs was observed in 25 % of patients. The mean annual cost of antipsychotic therapy was US$79.90 (8079 Pakistani rupees). Risperidone treatment cost was US$60.30 (PakRs 6095), constituting 52 % of the total monotherapy cost. The cost of SGAs was significantly higher than the cost of FGAs (p < 0.05). Conclusion: The results provide policymakers with appropriate information necessary for managing pharmacotherapy plans for the treatment of schizophrenia.

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Section: Discussionsupporting

confidence: 91%

Antipsychotic prescription patterns and treatment costs of schizophrenia in northwestern Pakistan: A one-year observational study

Khan¹,

Iqbal²,

Sultan³

et al. 2018

Trop. J. Pharm Res

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“…[15] Several nonpsychiatric conditions are also being treated with a wide variety of psychotropic drugs. [4] For example, antidepressants mainly amitriptyline are the widely accepted treatment for neuropathic pain. GI disturbances being the most common indication in the surgical wards could be due to the high use of antibacterial, anesthetics, and analgesics.…”

Section: Discussionmentioning

confidence: 99%

“…[1] The coexistence of depression and anxiety with chronic illnesses is very common. [1234567] Despite the accepted psychiatric indications, psychotropic is also being used in an off-labeled manner. [2] Therefore, there is a likelihood of receiving psychotropic drugs by physically ill populations.…”

Section: Introductionmentioning

confidence: 99%

“…[2] Therefore, there is a likelihood of receiving psychotropic drugs by physically ill populations. [4] Globally, psychotropic drugs are available only on prescriptions. Studies reported that nonpsychiatrists were responsible for the majority of psychotropic drug prescriptions, and most of these prescriptions were without a psychiatric diagnosis.…”

Section: Introductionmentioning

confidence: 99%

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A prospective observational study on psychotropic drug use in non psychiatric wards

Lucca

Vamsi

Kurian

et al. 2019

Indian J Psychiatry

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Background:Psychotropic medications are the first line for the management of psychiatric illnesses; in addition, they are also being used in an off-labeled manner. Inappropriate prescribing of psychotropic medications either can cause serious harm or may be of no benefit to the patients. However, there is a dearth of information on the pattern of psychotropic drug use in the nonpsychiatry wards.Aim:The aim of this study is to assess the use of psychotropic drugs in general medicine and surgical wards of a teaching hospital.Materials and Methods:An observational study was conducted in the general medicine and surgical wards of a university teaching hospital over 6 months. Patients admitted to the medicine and surgical ward were observed for a prescription of psychotropic medications. Once they were prescribed with a psychotropic medication, the patients were included in the study and were followed until discharge. All the necessary information such as dose, route, class of psychotropic and prescriber's status were documented and analyzed.Results:A total of 322 patients were prescribed with 452 psychotropic medications. The average number of psychotropic per patient was 1.40 ± 0.76 (range: 1–4). The rate of psychotropic medications prescription in the nonpsychiatric ward is 10.73%. Alcohol dependence syndrome (n = 90 [26.71%]) and pain (n = 43 [43.87%]) were the observed psychiatric and nonpsychiatric indications. The frequently prescribed psychotropic classes were benzodiazepines (n = 165 [36.50%]) and antidepressants (n = 144 [31.86%]). Nonpsychiatrists (n = 250 [55.3%]) were the common prescribers and benzodiazepines (n = 124 [27.43%]) were the preferred class for nonpsychiatrist, whereas psychiatrist prescribed different class of psychotropic drugs.Conclusion:This study emphasizes that nonpsychiatrist irrespective of their specialty prescribed psychotropic medication for psychiatric and nonpsychiatric indications.

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Prescribing pattern of psychotropic drugs used in non-psychiatric patients among outpatient department of two teaching hospitals in Bangladesh

Cited by 2 publications

References 12 publications

Antipsychotic prescription patterns and treatment costs of schizophrenia in northwestern Pakistan: A one-year observational study

Antipsychotic prescription patterns and treatment costs of schizophrenia in northwestern Pakistan: A one-year observational study

A prospective observational study on psychotropic drug use in non psychiatric wards

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