Prescripción inapropiada de antifúngicos y la necesidad de programas para su uso racional

Osorio-Lombana, Juan Pablo; Maldonado, Sonia Isabel Cuervo; López-Mora, María José; Gómez-Rincón, Julio César

doi:10.4067/s0716-10182019000400403

Cited by 1 publication

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“…Antifungal agents are overused or misused in humans [44] [45], animals [46], agriculture [47] [48], and other environmental sectors [49]. This overuse and misuse have contributed to the occurrence of AFR in the One Health ecosystem [50] [51]. On top of that, like other antimicrobial drugs [52] [53] [54] [55], antifungal agents are widely accessed without prescriptions [56].…”

Section: Introductionmentioning

confidence: 99%

Global Burden of Fungal Infections and Antifungal Resistance from 1961 to 2024: Findings and Future Implications

Mudenda

2024

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Background: Antifungal resistance (AFR) is a global public health problem with devastating effects, especially among immunocompromised individuals. Addressing AFR requires a One Health approach including Antifungal Stewardship (AFS). This study aimed to comprehensively review global studies published on fungal infections and AFR and to recommend solutions to address this growing problem. Materials and Methods: This was a narrative review that was conducted using published papers on fungal infections, AFR, and AFS between January 1961 and March 2024. The literature was searched using PubMed, Google Scholar, Web of Science, and EMBASE. Results: This found that there has been an increase in fungal infections globally, especially among immunocompromised patients. Due to this increase in fungal infections, there has been a proportionate increase in the use of antifungal agents to prevent and treat fungal infections. This increased use of antifungal agents has worsened the problem of AFR contributing to increased morbidity and mortality. Globally, fungal infections have contributed to 150 million infections annually and 1.7 million deaths per year. By the year 2023, over 3.8 million people died from fungal infections. Addressing AFR remains a challenge because the treatment of antifungal-resistant infections is difficult. Finally, the treatment of fungal infections is a global challenge exacerbated by the limited number of antifungal agents to treat invasive fungal infections. Conclusion: The results of this study indicated that fungal infections and AFR are prevalent across humans, animals, agriculture, and the environment. Addressing this problem requires the provision of solutions such as improving the awareness of AFR, conducting further research on the discovery of new antifungal agents, and implementing AFS programs. If this global problem is not addressed, the morbidity and mortality associated with AFR will continue to rise in the future.How to cite this paper: Mudenda, S.

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Section: Introductionmentioning

confidence: 99%

Global Burden of Fungal Infections and Antifungal Resistance from 1961 to 2024: Findings and Future Implications

Mudenda

2024

View full text Add to dashboard Cite

show abstract

Prescripción inapropiada de antifúngicos y la necesidad de programas para su uso racional

Cited by 1 publication

References 14 publications

Global Burden of Fungal Infections and Antifungal Resistance from 1961 to 2024: Findings and Future Implications

Global Burden of Fungal Infections and Antifungal Resistance from 1961 to 2024: Findings and Future Implications

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