Prevalence and Antimicrobial Resistance Pattern of Methicillin Resistant Staphylococcus aureus (MRSA) Strains Isolated from Clinical Specimen in Udaipur, Rajasthan

Gupta, Summit; Shah, R. V.

doi:10.31080/asmi.2019.02.0370

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…23,24 Prevalence rate of MRSA was observed in different countries of South Asia like Karachi 43% by Perwaiz S, Barakzi Q, Farooqi BJ et al, in, Nepal 38% and 40% by Tiwari HK, Das AK, Sapkota D et al, in and by Sanjana RK, Shah R, Chaudhary N et al, respectively which are lower when compared to the results. 23,25,26 Tremendous increase in the methicillin resistant isolates in the hospital was observed, when compared with the study of Yogesh Kumar Gupta, Garima gupta et al 27 This difference might be because they used oxacillin disc diffusion method for detection of MRSA on the other hand author used cefoxitin disc diffusion for the detection of MRSA.…”

Section: Resultsmentioning

confidence: 83%

Detection of inducible clindamycin resistance in Staphylococcus aureus from various samples in a tertiary care hospital

Kumar¹,

Jagarti

Sarma

et al. 2019

Int J Res Med Sci

View full text Add to dashboard Cite

Background: The increasing frequency of MRSA infections and rapidly changing patterns in antimicrobial resistance, led to renewed interest in the usage of Macrolides-Lincosamide-Streptogramin B (MLSB) antibiotics to treat Staphylococcus aureus infection. Clindamycin is an important drug used in the treatment of MRSA and MSSA infection. The aim of this study was to determine inducible and constitutive clindamycin resistance among clinical isolates of Staphylococcus aureus by D-test.Methods: During a period of 6 months from July 2018 to December 2018, a total of 100 Staphylococcus aureus isolated from different clinical samples were subjected to routine antibiotic sensitivity testing by Kirby Bauer’s disc diffusion method. Methicillin-resistance was determined by using the cefoxitin (30 µg) disc. Incidence of MLSBc and MLSBi in Staphylococcus aureus isolates by D-test as per CLSI guidelines.Results: Out of 100 isolates of Staphylococcus aureus obtained from 350 clinical samples, 70(70%) were found to be MRSA and 30(30%) were MSSA. Among 100 Staphylococcus aureus isolates, 40% isolates showed MLSBi resistance, 28% isolates showed MLSBc resistance, 6% isolates showed MS phenotype and 26% isolates showed Sensitive phenotype. MLSBc and MLSBi were found to be higher in MRSA as compared to MSSA (21%, 27% and 7%, 10% respectively). All clinical isolates showed 100% sensitivity to Vancomycin and Linezolid in routine antibiotic susceptibility testing.Conclusions: Continuous surveillance of the MLSB resistance is important and required before the prescription of clindamycin to treat MRSA infections.

show abstract