Prevalence and factors associated with uncomplicated storage and voiding lower urinary tract symptoms in community-dwelling Australian men

Martin, Sean; Haren, Matthew T.; Marshall, Villis R.; Lange, Kylie; Wittert, Gary

doi:10.1007/s00345-010-0605-8

Cited by 132 publications

(104 citation statements)

References 28 publications

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“…Among similar studies in men, one comparing 120 men with and 285 without LUTS, total, HDL, and LDL cholesterol as well as triglyceride levels measured after an overnight fast did not differ significantly between groups (Rohrmann et al 2005). However, among 1103 randomly selected, community-dwelling men from Australia, linear associations between storage LUTS and low HDL cholesterol were observed (Martin et al 2011). In a follow-up analysis of this cohort, greater HDL cholesterol and lower triglycerides were associated with improvement of storage LUTS, whereas lower HDL cholesterol at baseline was associated with progression of LUTS (Martin et al 2014).…”

Section: Clinical Associations Between Atherosclerosis Risk Factors Amentioning

confidence: 44%

“…In probably the largest study which was based on 9856 men with clinically diagnosed BPH, increasing IPSS was associated with a higher odds ratio for having a diagnosis of diabetes; conversely, men with diabetes had a greater IPSS and a smaller maximum urine flow rate (Michel et al 2000). Among 1103 Australian men, a linear association between storage LUTS and plasma glucose was observed (Martin et al 2011). Among 1206 participants of the control arm of the Air Force Health Study, a higher fasting blood glucose was associated with a greater risk for a diagnosis of BPH, but the relative risk was close to 1 (1.004; 95 % confidence interval 1.001-1.007) (Gupta et al 2006).…”

Section: Clinical Associations Between Atherosclerosis Risk Factors Amentioning

confidence: 61%

“…Thus, among 1206 mean in the comparison arm of the Air Force Health Study, greater systolic blood pressure was not associated with an increased risk of clinically diagnosed BPH (Gupta et al 2006). Similarly, among 1103 randomly selected, community-dwelling men from Australia, neither storage nor voiding LUTS were associated with systolic or diastolic blood pressure (Martin et al 2011). Thus, associations between male LUTS and hypertension were reported inconsistently and hence are inconclusive.…”

Section: Clinical Associations Between Atherosclerosis Risk Factors Amentioning

confidence: 91%

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Are blood vessels a target to treat lower urinary tract dysfunction?

Michel

Chess-Williams

Hegde

2015

Naunyn-Schmiedeberg's Arch Pharmacol

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Bladder dysfunction is common in the general population (Stewart et al. 2010) and even more so among patients seeing a physician for any reason (Goepel et al. 2002). It often manifests as lower urinary tract symptoms (LUTS), a term originally coined to describe voiding and storage symptoms in men with benign prostatic hyperplasia (BPH) but now more universally used to describe any type of voiding and storage symptoms in both sexes. Studies into possible causes of urinary bladder dysfunction have long focused on detrusor smooth muscle cells (Turner and Brading 1999). More recently, it became clear that several other types of cells and organs contribute to regulating detrusor smooth muscle function. These include the urothelium (Andersson and McCloskey 2014; Michel 2015), afferent nerves (Michel and Igawa 2015; Yoshimura et al. 2014b), and the central and autonomic nervous systems (Fowler and Griffiths 2010; Yoshimura et al. 2014a). Alterations in any of these may at least partly be responsible for detrusor dysfunction and, accordingly, be potential targets for the treatment of bladder dysfunction. As highlighted by an article in this issue of Naunyn-Schmiedeberg's Archives of Pharmacology (Bayrak et al. 2015), there is an additional suspect, the bladder vasculature. This article will discuss the currently available experimental and clinical evidence for a role of the vasculature in causing bladder dysfunction, and how existing and emerging treatments may modulate bladder function by acting on blood vessels. Due to a similarity in concept, data on prostate perfusion will also be discussed to some extent.

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Section: Clinical Associations Between Atherosclerosis Risk Factors Amentioning

confidence: 44%

Section: Clinical Associations Between Atherosclerosis Risk Factors Amentioning

confidence: 61%

Section: Clinical Associations Between Atherosclerosis Risk Factors Amentioning

confidence: 91%

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Are blood vessels a target to treat lower urinary tract dysfunction?

Michel

Chess-Williams

Hegde

2015

Naunyn-Schmiedeberg's Arch Pharmacol

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“…Принятая в качестве «золотого стандарта» терапия α-адреноблокаторами не всегда достигает жела-емого эффекта у пациентов из-за ряда осложнений: отек предстательной железы, снижение артериального давле-ния, головные боли, ретраградная эякуляция и т. д. [4][5][6][7]. В связи с этим для достижения оптимального терапевти-ческого эффекта важно применение растительного пре-парата на начальных стадиях заболевания как в моно-, так и в комбинированной терапии.…”

Section: Introductionunclassified

Effectiveness and Safety of the «de Alex» Bio Complex as Monotherapy and in Combination With Tamsulosin in Patients With Benign Prostatic Hyperplasia

Scheplev¹,

Ipatenkov²,

Наумов³

2017

Androl. genit. hir.

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Açık Prostatektomi Teknikleri

2015

Indications and Resection Methods of Prostate

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GirişAlt üriner sistem semptomları (AÜSS) erişkin erkeklerde en sık görülen semptomlardandır ve prevelansı yaşlanma ile artar [1,2]. Tahmini prevelans yaygın olarak kullanılan tanımlamalara ve örneklere bağlı olarak değişir, ama yaşlı erkeklerde en az bir AÜSS görüldüğü rapor edilmiştir. AÜSS depolama, işeme ve işeme sonrası semptomlarına ayrılır ve geleneksel olarak sıklıkla benign prostat obstrüksiyonu sonucu gelişen mesane çıkım obstrüksiyonu ile ilişkilidir [3,4]. Bu durum da histolojik olarak benign prostat hiperplazisinin (BPH) sonucunda gelişen benign prostatik büyüme ile ilişkilidir. BPH tedavisi denilince 20. yüzyıl başlarında açık prostatektomi ve transü-retral prostat rezeksiyonu (TUR-P) akla gelmekteydi, ancak son yıllarda medikal ve minimal invaziv tedavilerin popüler olması ile cerrahi işlem sıklığında azalma meydana gelmiştir. Ancak medikal tedavinin uzun dönem sonuçlarındaki başarısızlık ve ablasyon yapmayan tedavilerin yetersizliği nedeni ile cerrahi yöntemler son zamanlarda tekrar gündeme gelmeye başlamıştır. Genel olarak BPH için cerrahi girişim endikasyonları; 1-Kronik üriner retansiyon 2-Tekrarlayan üriner sistem enfeksiyonu 3-Medikal tedaviye yanıt vermeyen prostat kaynaklı kanama 4-BPO ya bağlı renal yetmezlik 5-Mesane taşları olarak sayılabilir.Açık prostatektomi en eski prostatektomi yöntemidir. İlk defa 1885 yılında Von Dittel tarafından bir doktora açık prostatektomi yapılmıştır. Hasta 6 gün sonra enfeksiyon ve ekstravazasyon sonucunda ölmüştür. Açık prostatektomi retropubik veya

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Prevalence and factors associated with uncomplicated storage and voiding lower urinary tract symptoms in community-dwelling Australian men

Abstract: The close association of storage LUTS with the metabolic syndrome, and of both storage and voiding LUTS with OSA, suggest that these conditions should be considered in men presenting with LUTS.

Cited by 132 publications

References 28 publications

Are blood vessels a target to treat lower urinary tract dysfunction?

Are blood vessels a target to treat lower urinary tract dysfunction?

Effectiveness and Safety of the «de Alex» Bio Complex as Monotherapy and in Combination With Tamsulosin in Patients With Benign Prostatic Hyperplasia

Açık Prostatektomi Teknikleri

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