Prevalence and Patterns of Marijuana Use in Young Adults With Inflammatory Bowel Disease

Phatak, Uma Padhye; Rojas‐Velasquez, Danilo; Porto, Anthony F.; Pashankar, Dinesh S.

doi:10.1097/mpg.0000000000001474

Cited by 47 publications

(49 citation statements)

References 14 publications

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“…Studies performed in adults were included as well. By handsearching, we finally included nine studies that evaluate cannabis treatment for adult patients with IBD [2][3][4][5][6][22][23][24][25] and one for adolescent IBD patients (13-21 years of age) [8]. These studies are shown in Table 1.…”

Section: Cannabis Use Among Adult Patients With Ibdmentioning

confidence: 99%

“…These studies are shown in Table 1. In summary, a high prevalence of cannabis use in adult and adolescent IBD patients is seen in various countries [2][3][4][5][6]. Many patients report beneficial effects of cannabis on IBD-related symptoms, as well as improvement of the quality of life.…”

Section: Cannabis Use Among Adult Patients With Ibdmentioning

confidence: 99%

“…This effect was not seen with cannabidiol [25]. A few side effects (panic attack, drowsiness, poor diet, lethargy, and addiction) of cannabis were reported by patients [3]. However, the safety profile of cannabis and cannabidiol in the treatment of IBD is poorly examined.…”

Section: Cannabis Use Among Adult Patients With Ibdmentioning

confidence: 99%

“…Population-based surveys show that many adult and adolescent IBD patients use cannabis to relieve abdominal symptoms [2][3][4][5][6]. About 10 -20 % of patients are still under the age of 18 years when diagnosed with IBD [1,7].…”

Section: Introductionmentioning

confidence: 99%

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Cannabis, a potential treatment option in pediatric IBD? Still a long way to go

Halbmeijer

Groeneweg

Ridder

2019

Expert Review of Clinical Pharmacology

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Introduction: The onset of inflammatory bowel disease (IBD) in children is rising. Current treatment options are based on immunomodulatory therapy. Alternative treatment options are upcoming since they appear to be effective in individual patients. Cannabis might relief IBD symptoms in these cases and improve quality of life. Recent evidence suggests a potential anti-inflammatory effect of cannabis. Areas covered: This review presents an overview of recent literature on the use of cannabis in IBD focussing on pediatric IBD patients. Background information on the role of the endocannabinoid system within the gastrointestinal tract is presented. Other modalities of cannabis and its purified ingredients will be discussed as well, with attention to its applicability in children with IBD. Expert opinion: More research is needed on the efficacy and safety of cannabis in pediatric IBD. Studies are well underway, but until then the use of cannabis in pediatric IBD cannot be recommended. ARTICLE HISTORY

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Section: Cannabis Use Among Adult Patients With Ibdmentioning

confidence: 99%

Section: Cannabis Use Among Adult Patients With Ibdmentioning

confidence: 99%

Section: Cannabis Use Among Adult Patients With Ibdmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Cannabis, a potential treatment option in pediatric IBD? Still a long way to go

Halbmeijer

Groeneweg

Ridder

2019

Expert Review of Clinical Pharmacology

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“…Cannabis/Cannabinoids in IBD The inflamed gut is highly amenable to treatment with cannabinoids, which is documented for human IBD not only by anecdotal reports but, importantly, also by several questionnaire studies [70][71][72][73] as well as observational studies and prospective clinical trials [74][75][76][77]. Many of the questionnaires have revealed that patients with IBD frequently self-medicate with Cannabis to alleviate abdominal pain and diarrhea.…”

Section: Are Cannabinoids a Therapeutic Option For Inflammation And Nmentioning

confidence: 99%

Medical Cannabis and Cannabinoids: An Option for the Treatment of Inflammatory Bowel Disease and Cancer of the Colon?

Grill

Hasenoehrl

Storr

et al. 2018

Med Cannabis Cannabinoids

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In the past few years, we have witnessed a surge of new reports dealing with the role of cannabinoids, synthetic as well as herbal, in the mechanisms of inflammation and carcinogenesis. However, despite the wealth of in vitro data and anecdotal reports, evidence that cannabinoids could act as beneficial drugs in inflammatory bowel disease (IBD) or in neoplastic development of the human gastrointestinal tract is lacking. Some insight into the effects of medical Cannabis (usually meaning dried flowers) and cannabinoids in IBD has been gained through questionnaires and small pilot studies. As to colorectal cancer, only preclinical data are available. Currently, Δ⁹-tetrahydrocannabinol (THC) and its synthetic forms, dronabinol and nabilone, are used as an add-on treatment to alleviate chronic pain and spasticity in multiple sclerosis patients as well as chemotherapy-induced nausea. The use of medical Cannabis is authorized only in a limited number of countries. None of the mentioned substances are currently indicated for IBD. This review is an update of our knowledge on the role of cannabinoids in intestinal inflammation and carcinogenesis and a discussion on their potential therapeutic use.

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