Prevalence and predictors of elevated central venous pressure and obstructive sleep apnea in patients with lower extremity chronic venous disease

Kolluri, Raghu; Bashir, Riyaz; Matros, Todd; Albers, Anne; Fowler, Brian; Frederick, Amanda; Gupta, Anand; Patil, Nirav; Davis, Paul G.

doi:10.1016/j.jvsv.2019.12.071

Cited by 7 publications

(2 citation statements)

References 28 publications

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“…6 Venous abnormalities including obstruction or reflux can result in chronic venous disease and VLU. [7][8][9] Concomitant factors such as obesity, elevated central venous pressures, 10 immobility, and reduced calf muscle pump function may exacerbate impaired venous return. data preclude similar recommendations for deep venous disease (DVD).…”

Section: Introductionmentioning

confidence: 99%

An estimate of the economic burden of venous leg ulcers associated with deep venous disease

et al. 2021

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Introduction: Venous leg ulcers (VLU) embody the most severe stage of the broad spectrum of chronic venous disease. Approximately 40% of patients with VLU present with the underlying deep venous disease (DVD). Although the data are scarce, these deep venous disease-related VLU (DRV) are thought to have higher recurrence rates and a substantial economic burden. The objective of this study was to assess the economic burden of DRV across Australia, France, Germany, Italy, Spain, the UK, and the USA. Methods: A comprehensive literature review was undertaken to identify publications documenting the incidence and prevalence of VLU and DRV, medical resource utilization, and associated costs of DRV. Findings from this literature review were used to estimate the economic burden of illness, including direct medical costs over a 12-month interval following initial presentation of a newly formed DRV. Results: Total annual incidence of new or recurrent DRV in Australia, France, Germany, Italy, Spain, UK, and the US are estimated at 122,000, 263,000, 345,000, 253,000, 85,000, 230,000, and 643,000 events, respectively, in 2019. Incidence ranges from 0.73 to 3.12 per 1000 persons per year. The estimated annual direct medical costs for patients managed conservatively in these geographies total ~ $10.73 billion (USD) or $5527 per person per year. Conclusion: The availability of published data on the costs of VLU care varies widely across countries considered in this analysis. Although country-specific VLU practice patterns vary, there is a uniform pattern of high-cost care.

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Section: Introductionmentioning

confidence: 99%

An estimate of the economic burden of venous leg ulcers associated with deep venous disease

et al. 2021

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“… Score = 4; high; study design, sample size, sample selection and data analyses, each scored 1. Kolluri et al, 2020 [ 37 ] United States Retrospective study 264 Chronic venous disease (CVD), diabetes mellitus, pulmonary embolism, renal insufficiency 22.7% of the patients had elevated central venous pressure (CVP) and 26.9% had OSA. There was no significant difference in the prevalence of OSA.…”

Section: Methodsmentioning

confidence: 99%

Association and Risk Factors for Obstructive Sleep Apnea and Cardiovascular Diseases: A Systematic Review

2021

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Obstructive sleep apnea (OSA) is a serious, potentially life-threatening condition. Epidemiologic studies show that sleep apnea increases cardiovascular diseases risk factors including hypertension, obesity, and diabetes mellitus. OSA is also responsible for serious illnesses such as congestive heart failure, stroke, arrhythmias, and bronchial asthma. The aim of this systematic review is to evaluate evidence for the association between OSA and cardiovascular disease morbidities and identify risk factors for the conditions. In a review of 34 studies conducted in 28 countries with a sample of 37,599 people, several comorbidities were identified in patients with severe OSA—these were: heart disease, stroke, kidney disease, asthma, COPD, acute heart failure, chronic heart failure, hyperlipidemia, thyroid disease, cerebral infarct or embolism, myocardial infarction, and psychological comorbidities including stress and depression. Important risk factors contributing to OSA included: age > 35 years; BMI ≥ 25 kg/m2; alcoholism; higher Epworth sleepiness scale (ESS); mean apnea duration; oxygen desaturation index (ODI); and nocturnal oxygen desaturation (NOD). Severe OSA (AHI ≥ 30) was significantly associated with excessive daytime sleepiness and oxygen desaturation index. The risk of OSA and associated disease morbidities can be reduced by controlling overweight/obesity, alcoholism, smoking, hypertension, diabetes mellitus, and hyperlipidemia.

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The prevalence of poor sleep quality and its association with the risk of obstructive sleep apnea and restless legs syndrome in diabetic patients treated with cyanoacrylate glue for varicose veins

Demirtaş

Dolu

2022

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Prevalence and predictors of elevated central venous pressure and obstructive sleep apnea in patients with lower extremity chronic venous disease

Cited by 7 publications

References 28 publications

An estimate of the economic burden of venous leg ulcers associated with deep venous disease

An estimate of the economic burden of venous leg ulcers associated with deep venous disease

Association and Risk Factors for Obstructive Sleep Apnea and Cardiovascular Diseases: A Systematic Review

The prevalence of poor sleep quality and its association with the risk of obstructive sleep apnea and restless legs syndrome in diabetic patients treated with cyanoacrylate glue for varicose veins

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