Prevalence, Distribution and Factors Associated with the Presence and the Potential for Malignancy of Cutaneous Neoplasms in 174 Dogs Admitted to a Clinic in Northern Greece

Abstract

One hundred and seventy-four dogs diagnosed with cutaneous neoplasms in the Animal Medical and Surgical Clinic, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, were studied. Thirty-one types of neoplasm were diagnosed, among which mast cell tumours (13.8%), hepatoid gland adenomas (9.8%), lipomas (5.7%) and histiocytomas (5.7%) were the most common. The prevalence of epithelial, mesenchymal, lymphohistiocytic and melanocytic tumours was 47.7, 40.8, 8.6 and 2.9%, respectively. Potentially malignant neoplasms were less frequently recorded than benign neoplasms. The tumours were single (80.5%) or multiple (19.5%) and located on the head and neck (18.4%), the body trunk (49.4%), the limbs (25.9%) or at multiple sites (6.3%). The factors evaluated in multivariable logistic regression models for possible association with the odds of a tumour's potential for malignancy included the age, the sex and the breed of the dog, as well as the histological type of the neoplasm. Dogs with mesenchymal tumours had two times higher odds of potential for malignancy than those with epithelial tumours. In contrast, dogs with either lymphohistiocytic or melanocytic tumours did not have increased risk of malignancy compared with dogs with epithelial tumours. The odds of tumour malignancy linearly increased with increasing age of the dog by a factor of 1.1 per year. Finally, the eect of the sex and the breed of the dog on the risk of developing cutaneous neoplasms was investigated in an age-matched case±control sample of 348 dogs by conditional logistic regression analysis. The odds of neoplasm presence were two times higher in pure bred dogs than in mongrels but did not dier between cross-breeds and mongrels. U. S.

Histomorphological and immunohistochemical characterization of 172 cutaneous round cell tumours in dogs

“…In this study, the frequency of CLs was higher than HCTs. Studies on the prevalence of skin tumours in dogs show that the frequency of HCTs is greater than CLs, but in these cases, only histology was used as a diagnostic tool (Kaldrymidou et al 2002, Pakhrin et al 2007). The diagnosis of PCT, LHS and TVT using IHC (5.2%, 9/172, 3.5%, 6/172 and 4.1%, 7/172, respectively) was greater than the diagnoses using only histology (1.74%, 3/172, 1.17%, 2/172 and 0.06%, 1/172, respectively).…”

Prevalência de neoplasmas cutâneos em cães da região metropolitana de Porto Alegre, RS: 1.017 casos (2002-2007)

“…Foi observado um maior número de neoplasmas cutâneos malignos do que benignos, resultado também identificado por Kaldrymidou et al (2002). Entretanto, difere de outros trabalhos de tumores cutâneos que apresentaram maior prevalência de benignos (Dobson et al 2002, Bellei et al 2006, Souza et al 2006, Pakhrin et al 2007.…”

“…Mastocitoma, lipoma, adenoma perianal, carcinoma de células escamosas, tricoblastoma e histiocitoma são alguns dos tumores cutâneos mais frequentes em cães (Rothwell 1987, Dobson et al 2002, Kaldrymidou et al 2002, Bellei et al 2006, Murphy 2006b, Souza et al 2006, Pakhrin et al 2007.…”

A Gigantic Cutaneous Fibroadenoma in a Dog

“…In this respect, Kaldrymidou et al (2002) observed that the odds of neoplasm presence were two times higher in pure bred dogs than in mongrels but did not differ between cross-breeds and mongrels.…”

“…Histopathologically, the recorded tumor was confirmed as fibroadenoma with a tendency of malignancy. In this respect, the odds of tumor malignancy linearly increased with increasing age by a factor of 1.1 per year (Kaldrymidou et al, 2002).…”