Prevalence of obstructive sleep apnea–hypopnea in severe versus moderate asthma

Asthma outcomes improve with continuous positive airway pressure for obstructive sleep apnea

“…OSAS is an important risk factor for uncontrolled asthma and for frequent exacerbations 7, 8, 9, 10, 11. In a prospective study of 22 patients with difficult‐to‐control asthma, a night polysomnography showed that all but one patient had OSAS (95.5% prevalence) 7.…”

“…In a prospective study of 22 patients with difficult‐to‐control asthma, a night polysomnography showed that all but one patient had OSAS (95.5% prevalence) 7. Also, it has been shown that the prevalence of OSAS increased progressively according to severity of asthma (from 58% in moderate asthma to 88% in severe asthma) 9. In children with poorly controlled asthma and frequent asthmatic exacerbations, the prevalence of OSAS was markedly increased (63%) 10.…”

Prevalence of Obstructive Sleep Apnea-Hypopnea in Severe Asthma

“…The most recent studies have been based on polysomnography as a baseline test to determine the prevalence of OSAS in asthmatics, like the Canadian study by Julien et al comparing the prevalence of OSAS in 3 groups of patients: Severe asthma, 2 nd moderate asthma and 3 rd non-asthmatic subjects. This prevalence was 50%, 23% and 12% (0.007), respectively, and there was no correlation between the severity of asthma and the severity of OSAS [7] A recent study by Shaarawy et al found an OSAS prevalence of 25% in 60 patients followed for uncontrolled asthma [8] Min Kwang Byun et al published a study concluding a prevalence of OSAS of 66.5% in moderate to severe asthmatics [9] The majority of studies have considered OSAS as a factor in the poor control of asthma through various mechanisms, including sleep disorders, upper respiratory tract edema and systemic inflammation associated with OSAS. [10] On the other hand Some authors have tried to analyze the influence of asthma on the occurrence and severity of OSAS and have concluded that asthma may contribute to the onset and aggravation of OSAS by altering anatomy and physiology Of the upper airways [11] In our study, all patients had moderate to severe persistent asthma that was difficult to control and there was no correlation between the clinical characteristics of the asthmatic disease and the prevalence or severity of OSAS These results are similar to those of Auckley et al who did not find a correlation between the risk of OSAS occurrence and the severity of asthma [4] Guven et al made the same findings On the other hand, Teodorescu, et al demonstrated that a high risk of OSAS did not depend on other known factors of poor asthma control or control level (ACT) [5].…”

Association of Childhood Asthma and Pediatric Obstructive Sleep Apnea: A Retrospective Cohort Study from a Nationwide Population-based Database

“…Teodorescu et al reported that the association between asthma and OSA was significantly dose dependent on the duration of asthma [15]. Julien et al also reported that obstructive sleep apnea-hypopnea was significantly more prevalent among patients with severe compared with moderate asthma [24]. In our study, we did not know if the severity of asthma is the risk of subsequent OSA, but only know that the frequency of medical visits per year, which meaning the poor control of childhood asthma, increases the risk of subsequent OSA.…”