Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study

Al-Dahshan, Ayman; Al-Kubiasi, Noora; Al-Zaidan, Manal; Saeed, Wael; Kehyayan, Vahe; Bougmiza, Iheb

doi:10.1371/journal.pone.0234386

Cited by 28 publications

(29 citation statements)

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“…The PHC as the main mediator in the elderly's health, especially when they have chronic morbidities, such as hypertension, has elements that can increase the attendance of the elderly in the practice of physical activity and dietary reeducation, supported by health education, mainly in units that have other health professionals, such as nutritionists, psychologists and physical educators as matrix support. It is important to offer parameters that support the reflection and change in lifestyle and diet habits of this population with hypertension through interprofessional interventions, mainly health education (25)(26) .…”

Section: Discussionmentioning

confidence: 99%

“…Scientific evidence on cigarette use is associated with inadequate lifestyle habits and the chances of having a compromised nutritional profile. The role of the health professional, especially the prescribers of medication in PHC, is the responsibility of the individualized care settings, in which we can reduce the possibility of the iatrogenic cascade occurring in the elderly, caused by polypharmacy (22,26) .…”

Section: Discussionmentioning

confidence: 99%

“…Concerning polypharmacy, it is inherent to the aging process and is connected to the health needs of this population, which often has more than one morbidity, including diseases related to the central nervous system and inappropriate lifestyle habits, such as physical inactivity and inadequate diet. The sum of these factors provides multiple medication prescriptions, which may be related to PIM, mainly in PHC (7,(22)(23)26,(28)(29) .…”

Section: Discussionmentioning

confidence: 99%

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Factors associated with the use of potentially inappropriate medications by elderly people with hypertension

et al. 2020

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Objective: to analyze factors associated with the use of potentially inappropriate medications by elderly people with hypertension. Method: a cross-sectional study, conducted in the first semester of 2016, with elderly people undergoing treatment for hypertension, living in the city of Maringá. Interviews, medical records analysis, and measurement of clinical and anthropometric parameters of the participants were carried out. Inferential analysis was used. Results: a total of 260 elderly people who used potentially inappropriate medications participated in the study. The high use of these medications was associated with clinical and anthropometric conditions, such as obesity (p=0.022), smoking (p=0.004), polypharmacy (p=0.034) and the health services provided, such as organizationally accessible treatment (p=0.027) and consultation time (p=0.007), predisposing to low adherence to routine consultations (p=0.003). Conclusion: it was shown that the factors associated with the use of potentially inappropriate medications were associated with anthropometric, clinical, and organizational variables, intrinsic to the family health strategy.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Factors associated with the use of potentially inappropriate medications by elderly people with hypertension

et al. 2020

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“…As most chronic diseases typical for older adults are prevented and treated using pharmacotherapy, elderly patients are nearly automatically at high risk of multidrug therapy (Al-Dahshan et al, 2020;Panda et al, 2020). Thus, an older age is a risk factor for chronic polypharmacy (Wastesson et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Age Structure of Polypharmacy in Poland: Results of the Analysis of the National Real-World Database of 38 Million Citizens

Kardas

Urbański²,

Lichwierowicz³

et al. 2021

Front. Pharmacol.

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Introduction: Polypharmacy is a risk factor for adverse health outcomes, higher use of medical services and additional costs. The problem has gained attention as a consequence of aging and related multimorbidity. Therefore, there is an urgent need to adopt effective interventions aimed at reducing its burden. In order to achieve this, in-depth understanding of the prevalence of polypharmacy is required. Of particular interest is, however, assessing prevalence of polypharmacy in various age groups, to reach the right target for these interventions. So far, only limited data on polypharmacy among non-elderly individuals have been available.Aim of study: To assess overall prevalence of polypharmacy in Poland as well as its distribution in various age groups using real-world data.Methodology: A retrospective analysis of complete dispensation data of national payer organization for the years 2018–2019. The analyzed dataset included data on dispensation of reimbursed drugs, and exclusively for 2019, also non-reimbursed drugs. Polypharmacy was defined as dispensation of ≥5 prescription medications within six months.Results: In the analyzed national cohort of 38 million Polish citizens, the prevalence of polypharmacy was found to be 11.7% in 2018 and 11.6% in 2019. With age, the prevalence of polypharmacy increased, reaching the value of 56.0% in those aged 80+ in 2018, and 55.0% in 2019. Altogether, among those aged 65+, the polypharmacy was present in 43.1% in 2018, and 42.1% in 2019. In the youngest group of citizens, i.e., among those aged below 20 years, polypharmacy was found in 0.9%, and 0.8% in 2018 and 2019, respectively. Prevalence of polypharmacy, calculated for 2019 according to dispensation of five or more reimbursed and non-reimbursed drugs for the whole Polish population, was 21.8% for January-June, and 22.4% for July-December 2019. Among those aged 65+, the relevant numbers were 62.3%, and 62.9%, respectively.Conclusion: This study, being the first nationwide assessment of polypharmacy in Poland, confirmed its high prevalence. We found polypharmacy present in over one fifth of Polish society. Peaking in the elderly, polypharmacy occurred in each age group. These results lay the foundations for future interventions focused on reducing the scope of this problem in Poland.

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“…Aging population results to the increase of chronic diseases and subsequent comorbidities that require concomitant multiple medications. It is reported that about 80 % of elderly have at least one chronic condition, and about half of them have at least two (such as heart disease, hypertension, diabetes mellitus (DM), arthritis, and cancer) [1]. Besides, it is estimated that almost 39 % of the elderly take ≥ 5 medications and about 72 % of this population take at least one nonprescription medication (OTC) [2,3].…”

Section: Introductionmentioning

confidence: 99%

Поліпрагмазія У Людей Похилого Віку: Поширеність, Наслідки Та Стратегія Профілактики

Kotsalou

2021

Mìžnarodnij endokrinologìčnij žurnal

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Aging is a status often associated with multiple comorbidities which require pharmacologic intervention and complex medication regimens. Aging population results to the increase of chronic diseases and subsequent comorbidities that require concomitant multiple medications. It is reported that about 80 % of elderly have at least one chronic condition, and about half of them have at least two (such as heart disease, hypertension, diabetes mellitus, arthritis, and cancer). According the literature the worldwide polypharmacy prevalence has a wide range (between 5 to 78 %) due to different definitions on the number of medications taken (ranging between 2 and 9) and the different samples studied. In most studies polypharmacy was more common between women and in more elderly people. Many multicenter studies have been performed to define the term of polypharmacy and its prevalence in the elderly population. Polypharmacy is of growing concern for the older adults, because it can be very dangerous for this population due to altered absorption, distribution, metabolism and excretion of the drugs within their body reflecting unexpected pharmacokinetics and pharmacodynamics of various medications. This fact can lead to adverse drug reactions (ADR), drug interactions, noncompliance and reduced adherence, reduced functional status, geriatric syndromes, high risk of hospitalization and possible death. Over the last decade, there are several evaluation tools which can help the General Practitioner prevent the polypharmacy in the elderly. As prescribing for this group of individuals is a very challenging procedure, the General Practitioner should balance between under-treatment, over-treatment and risks and benefits. This review concluded that we need more cross-sectional clinical studies on practical preventive interventions to be applied not only on the population which is already exposed to polypharmacy, but also to the general population.

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Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study

Cited by 28 publications

References 28 publications

Factors associated with the use of potentially inappropriate medications by elderly people with hypertension

Factors associated with the use of potentially inappropriate medications by elderly people with hypertension

Prevalence and Age Structure of Polypharmacy in Poland: Results of the Analysis of the National Real-World Database of 38 Million Citizens

Поліпрагмазія У Людей Похилого Віку: Поширеність, Наслідки Та Стратегія Профілактики

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