Prevalence of unprotected anal intercourse among HIV-diagnosed MSM in the United States: a meta-analysis

Crepaz, Nicole; Marks, Gary; Liau, Adrian; Mullins, Mary M.; Aupont, Latrina W.; Marshall, Khiya J.; Jacobs, Elizabeth D.; Wolitski, Richard J.

doi:10.1097/qad.0b013e32832effae

Cited by 208 publications

(201 citation statements)

References 56 publications

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“…Second, our models assume unbiased recall of sexual behaviors and reporting of those behaviors to clinicians prescribing PrEP. To the extent that behaviors would be underreported [40], this could overestimate PrEP performance. Third, many of the underlying sexual behaviors, the basis of the modeled PrEP indications in these models, have been parameterized from 2 studies on MSM in Atlanta.…”

Section: Discussionmentioning

confidence: 99%

Impact of the Centers for Disease Control's HIV Preexposure Prophylaxis Guidelines for Men Who Have Sex With Men in the United States

Jenness¹,

Goodreau²,

Rosenberg³

et al. 2016

J Infect Dis.

186

178

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Background. Preexposure prophylaxis (PrEP) is effective for preventing human immunodeficiency virus (HIV) infection among men who have sex with men (MSM) within trial settings. Population impact will depend on clinical indications for PrEP initiation, coverage levels, and drug adherence. No modeling studies have estimated the impact of clinical practice guidelines for PrEP issued by the Centers for Disease Control and Prevention (CDC).Methods. Mathematical models of HIV transmission among MSM were used to estimate the percentage of infections averted (PIA) and the number needed to treat (NNT) under behavioral indications of the CDC's PrEP guidelines. We modeled the contribution of these indications while varying treatment coverage and adherence.Results. At 40% coverage of indicated MSM over the next decade, application of CDC guidelines would avert 1162 infections per 100 000 person-years, 33.0% of expected infections. The predicted NNT for the guidelines would be 25. Increasing coverage and adherence jointly raise the PIA, but reductions to the NNT were associated with better adherence only.Conclusions. Implementation of CDC PrEP guidelines would result in strong and sustained reductions in HIV incidence among MSM in the United States. The guidelines strike a good balance between epidemiological impact (PIA) and efficiency (NNT) at plausible scale-up levels. Adherence counseling could maximize public health investment in PrEP by decreasing the NNT.

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Section: Discussionmentioning

confidence: 99%

Impact of the Centers for Disease Control's HIV Preexposure Prophylaxis Guidelines for Men Who Have Sex With Men in the United States

Jenness¹,

Goodreau²,

Rosenberg³

et al. 2016

J Infect Dis.

186

178

View full text Add to dashboard Cite

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“…Offers for informal HIV testing are given including voluntary testing and counseling (VTC), like point-of-care testing. Knowledge about a person's HIV + status is important, but its implementation for responsible behavior in reality is another story (Crepaz et al, 2009). Such an attitude has to be seen in the context of the long latency period during which the HIV can be transmitted to others.…”

Section: Strategies For Preventing the Spread Of Hivmentioning

confidence: 99%

Dilemma of concepts and strategies for the prevention of spread of HIV in relation to human behavior, law and human rights

Dennin

Lafrenz

Sinn

et al. 2011

J. Zhejiang Univ. Sci. B

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Abstract:The new prevalence data regarding the estimated global number of human immunodeficiency virus positive (HIV + ) cases, i.e., including people who are either aware or unaware of their HIV infection in 2010, lead many to wonder why the increase in incidence has reached today's unprecedented level and escalated within such a short time. This, in spite of prevention campaigns in countries affected by HIV/acquired immune deficiency syndrome (AIDS) with their urgent messages aimed at preventing HIV transmission by promoting changes in individual's behavior. This article analyzes the background of the prevention strategies, in particular their political, social and legal concepts in terms of human rights, and reveals traits of human behavior not considered thus far. A radical reappraisal is necessary, at social and legislative levels, as well as options additional to current concepts. When ethical issues come up, they become blamed for outmoded moralistic positions. However, ignoring the reality has led to dire consequences from prioritizing individual human rights over society's collective need to prevent the spread of HIV.

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“…While the HIV surveillance regulations established in the HPPA are, according to Section 2 of this Act, supposed to prevent the spread of disease, requirements for name-based surveillance may actually undermine HIV prevention efforts and compromise the health status of people living with HIV. Indeed, preventing access to HIV treatment until a person undergoes testing using his/her name negates two benefits associated with these medications: HIV treatments both improve the quality and quantity of life for people living with HIV and they decrease future HIV transmission (Miller et al 2010;Granich et al 2010;Hamlyn et al 2010;Pinkerton, Holtgrave and Galletly 2009;Crepaz et al 2009). Considering public health surveillance as an activity that is, in and of itself, a worthwhile and sufficiently justifiable activity sheds further light on the scope and nature of surveillance in contemporary society: in addition to being pervasive, surveillance appears to be accepted not as a mechanism to induce secondary outcomes, but rather, simply as a natural aspect of social life.…”

Section: Hiv Surveillance As a Self-limiting Processmentioning

confidence: 99%

Resisting Public Health Surveillance: Anonymous HIV Testing and the Imperative of Health

O’Byrne

Bryan

2013

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To date, there has been little research published about public health HIV surveillance, HIV testing, and HIV prevention. Accordingly, an exploratory project was undertaken, involving, firstly, a detailed review of local public health legislation and practice guidelines, and, secondly, the distribution of surveys about self-reported sexually transmitted infections (STI) and HIV testing/diagnosis, HIV testing practices, and sexual behaviours among gay, bisexual, and other men who have sex with men.

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Prevalence of unprotected anal intercourse among HIV-diagnosed MSM in the United States: a meta-analysis

Cited by 208 publications

References 56 publications

Impact of the Centers for Disease Control's HIV Preexposure Prophylaxis Guidelines for Men Who Have Sex With Men in the United States

Impact of the Centers for Disease Control's HIV Preexposure Prophylaxis Guidelines for Men Who Have Sex With Men in the United States

Dilemma of concepts and strategies for the prevention of spread of HIV in relation to human behavior, law and human rights

Resisting Public Health Surveillance: Anonymous HIV Testing and the Imperative of Health

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