Prevalence, symptoms and risk factor profile of rumination syndrome and functional dyspepsia: a population‐based study

Irani, Mudar Zand; Jones, Michael; Halland, Magnus; Herrick, Linda M.; Choung, Rok Seon; Loftus, Yuri A. Saito; Walker, Marjorie M.; Murray, Joseph A.; Talley, Nick

doi:10.1111/apt.16630

Cited by 23 publications

(18 citation statements)

References 103 publications

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“…Other relevant items in the clinical history include previous surgical interventions, due to misattribution of the symptoms of FD to other causes, such as gallstones,123 and the presence of other non-gastrointestinal chronic painful or ‘functional’ disorders,124 125 which support a diagnosis of FD. It is also important to ensure there is no family history of gastro-oesophageal cancer, inflammatory bowel disease, or coeliac disease.…”

Section: Presentation Of Fd Diagnosis and Management In Primary Carementioning

confidence: 99%

British Society of Gastroenterology guidelines on the management of functional dyspepsia

Black

Paine

Agrawal

et al. 2022

Gut

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Functional dyspepsia (FD) is a common disorder of gut–brain interaction, affecting approximately 7% of individuals in the community, with most patients managed in primary care. The last British Society of Gastroenterology (BSG) guideline for the management of dyspepsia was published in 1996. In the interim, substantial advances have been made in understanding the complex pathophysiology of FD, and there has been a considerable amount of new evidence published concerning its diagnosis and classification, with the advent of the Rome IV criteria, and management. The primary aim of this guideline, commissioned by the BSG, is to review and summarise the current evidence to inform and guide clinical practice, by providing a practical framework for evidence-based diagnosis and treatment of patients. The approach to investigating the patient presenting with dyspepsia is discussed, and efficacy of drugs in FD summarised based on evidence derived from a comprehensive search of the medical literature, which was used to inform an update of a series of pairwise and network meta-analyses. Specific recommendations have been made according to the Grading of Recommendations Assessment, Development and Evaluation system. These provide both the strength of the recommendations and the overall quality of evidence. Finally, in this guideline, we consider novel treatments that are in development, as well as highlighting areas of unmet need and priorities for future research.

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Section: Presentation Of Fd Diagnosis and Management In Primary Carementioning

confidence: 99%

British Society of Gastroenterology guidelines on the management of functional dyspepsia

Black

Paine

Agrawal

et al. 2022

Gut

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“…Functional dyspepsia (FD) is one of the most common types of functional gastrointestinal diseases (FGIDs) in clinical practice, with a high prevalence affecting 10%–30% of adults and 3.5%–27% of children worldwide ( Drago et al, 2021 ). The main clinical symptoms of patients are early satiety, postprandial discomfort, epigastric pain, epigastric distension, epigastric burning, loss of appetite, belching, nausea, and vomiting, which are often accompanied by anxiety and depression ( Potter and Talley, 2020 ; Zand et al, 2021 ). It not only affects the life and work of patients, but also brings economic pressure to patients and national medical services.…”

Section: Introductionmentioning

confidence: 99%

The Role of Gastrointestinal Microbiota in Functional Dyspepsia: A Review

Zhou¹,

Zeng

Zhang

et al. 2022

Front. Physiol.

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Functional dyspepsia is a clinically common functional gastrointestinal disorder with a high prevalence, high impact and high consumption of medical resources. The microbiota in the gastrointestinal tract is a large number of families and is one of the most complex microbial reservoirs in the human body. An increasing number of studies have confirmed the close association between dysbiosis of the gastrointestinal microbiota and the occurrence and progression of functional dyspepsia. Therefore, we reviewed the role of dysbiosis of the gastrointestinal microbiota, H. pylori infection and gastrointestinal microbiota metabolites in functional dyspepsia, focusing on the possible mechanisms by which dysbiosis of the gastrointestinal microbiota contributes to the pathogenesis of functional dyspepsia. Several studies have confirmed that dysbiosis of the gastrointestinal microbiota may cause the occurrence and progression of functional dyspepsia by disrupting the biological barrier of the intestinal mucosa, by disturbing the immune function of the intestinal mucosa, or by causing dysregulation of the microbial-gut-brain axis. Probiotics and antibiotics have also been chosen to treat functional dyspepsia in clinical studies and have shown some improvement in the clinical symptoms. However, more studies are needed to explore and confirm the relationship between dysbiosis of the gastrointestinal microbiota and the occurrence and progression of functional dyspepsia, and more clinical studies are needed to confirm the therapeutic efficacy of microbiota modulation for functional dyspepsia.

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“…As one of the four functional gastroduodenal disorders, FD has a high prevalence and affects a wide age range ( 21 ). Gender, whether or not they smoke, and whether or not they suffer from depression are all influential factors in triggering their symptoms ( 22 – 24 ). FD has been a major concern in the field of functional gastrointestinal disorders because of its serious impact on the quality of life and physical and mental health of patients.…”

Section: Discussionmentioning

confidence: 99%

Bibliometric analysis of functional dyspepsia research trends over the past 20 years

Wang

Líu

et al. 2022

Front. Public Health

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BackgroundFunctional dyspepsia is one of the most common functional gastrointestinal disorders that affects the physical health and quality of life of many people. Its status as a chronic disease has received continued attention in the field of gastrointestinal research.ObjectiveBibliometric methods using network analysis were used to identify developments and research trends in functional dyspepsia with a view to informing and orienting further in-depth research on functional dyspepsia.MethodBibliometric methods were used to analyze the documents on functional dyspepsia published from 2002 to 2022 retrieved from Web of Science Core Collection on 1 July 2022, import literature data into Excel and VOSviewer, and extract relevant information to analyze and visualize the annual number of publications, authors, organizations, countries, journals published, citations, and keywords.ResultsA total of 3,532 documents were retrieved, and the abstracts of each remaining documents were read one by one after four duplicate documents were removed, and 2,220 documents were included after screening, with a fluctuating growth trend. Tack J ranked first with 171 documents, followed by Talley NJ (n = 167). The top three organizations in terms of number of publications were Katholieke Universiteit Leuven (n = 131), Mayo Clinic (n = 127), and the University of Newcastle (n = 91). The most prolific country was the United States with 499 documents. The three journals with the highest number of publications are “Neurogastroenterology and Motility” (n = 218), “Alimentary pharmacology & therapeutics” (n = 101), and “Journal of Gastroenterology and Hepatology” (n = 90). The top three most cited documents were “Functional gastroduodenal disorders,” “Childhood Functional Gastrointestinal Disorders: Child/Adolescent,” and “The Serotonin Signaling System: From Basic Understanding to Drug Development for Functional GI Disorders.” Frequency counts and network co-occurrences of keywords reveal trends in this field, including “gastric emptying,” “anxiety,” “acupuncture,” and “ghrelin.”ConclusionThe study of the mechanism of gut–brain interaction in functional dyspepsia and the combination of non-pharmacological treatment and pharmacological treatment may be the future research hotspots and trends. Our findings are helpful to comprehensively review the research history of FD and provide reference for researchers in this field to further study.

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Prevalence, symptoms and risk factor profile of rumination syndrome and functional dyspepsia: a population‐based study

Cited by 23 publications

References 103 publications

British Society of Gastroenterology guidelines on the management of functional dyspepsia

British Society of Gastroenterology guidelines on the management of functional dyspepsia

The Role of Gastrointestinal Microbiota in Functional Dyspepsia: A Review

Bibliometric analysis of functional dyspepsia research trends over the past 20 years

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