Priapism as the presenting feature of renal cell carcinoma

Abstract

We describe a case of renal cell carcinoma with metastasis to the penis clinically presenting with priapism. Six such cases found in the literature are reviewed. Neoplastic disease is far advanced in these cases and therapy is only palliative.

Renal Cell Carcinoma Metastasis to the Penis: A Case Report and Literature Review

“…Among the documented cases, the left kidney was identified as the primary site of carcinoma in more than half of the instances [9]. However, in this patient, although the right kidney was identified as the primary site of carcinoma, the aggressive nature of the tumor and the presence of tumor thrombosis may have contributed to the occurrence of metastasis to the penis.…”

Malignant priapism as the initial presentation induced by the metastasis of renal clear cell carcinoma after radical nephrectomy

“…Many of the previously reported cases of priapism secondary to RCC were delayed the diagnosis, illustrating the importance of maintaining a high degree of clinical suspicion on malignant priapism. 2 The key point of diagnosis is obtaining the tissue for pathological examination.…”

“…Of the reported cases, left kidney was identified as the primary site of carcinoma in more than half cases. 2 It has been explained that RCC metastasizing to penis via retrograde venous flow seems a likely etiology despite the spermatic vein do not normally anastomose with the dorsal venous system. 2 , 3 In addition, the primary RCC of this Case contained two components, clear cell RCC and papillary RCC.…”

“… 2 It has been explained that RCC metastasizing to penis via retrograde venous flow seems a likely etiology despite the spermatic vein do not normally anastomose with the dorsal venous system. 2 , 3 In addition, the primary RCC of this Case contained two components, clear cell RCC and papillary RCC. However, the clear cell RCC, not papillary RCC, metastasized to penis.…”