2021
DOI: 10.1007/s12105-021-01324-6
|View full text |Cite
|
Sign up to set email alerts
|

Primary Alveolar Soft Part Sarcoma of Cheek: Report of a Case and Review of the Literature

Abstract: Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma characterized by an alveolar or organoid arrangement of polygonal tumour cells separated by fibrovascular septa. A specific fusion gene [ASPS critical region 1 (ASPSCR1)-TFE3] was detected in ASPS. Despite being a slow-growing tumour without pain and dysfunction, ASPS is characterized by early metastasis, which leads to poor prognosis. Herein, we report a rare case of primary ASPS of the cheek harbouring ASPSCR1 (exon 7)-TFE3 (exon 5) fusion gene … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4

Citation Types

0
4
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 2 publications
(4 citation statements)
references
References 19 publications
0
4
0
Order By: Relevance
“…The cells are separated by vascularized septa lined by endothelial cells, and focal necrosis may also be seen in the center of the nests with a pseudovascular pattern. The cytoplasm of these cells can be described as eosinophilic, with a clear appearance with uniform and centrally located nuclei [12][13][14]. A notable characteristic feature of this tumor is also a PAS and diastase-resistant rhomboid-shaped crystal, which is reported in up to 80% of cases [13].…”
Section: Discussionmentioning
confidence: 89%
See 3 more Smart Citations
“…The cells are separated by vascularized septa lined by endothelial cells, and focal necrosis may also be seen in the center of the nests with a pseudovascular pattern. The cytoplasm of these cells can be described as eosinophilic, with a clear appearance with uniform and centrally located nuclei [12][13][14]. A notable characteristic feature of this tumor is also a PAS and diastase-resistant rhomboid-shaped crystal, which is reported in up to 80% of cases [13].…”
Section: Discussionmentioning
confidence: 89%
“…Grossly, ASPS is usually characterized by a well-circumscribed lesion that has a soft and rubbery consistency and can vary in color from yellow to gray to tan; areas of necrosis and hemorrhage can also be demonstrated [ 12 , 13 ]. The size of ASPS can range in presentation from 1.2 cm to 24 cm, with a mean size of 6.5 cm, and variability depends on the primary tumor site [ 9 ].…”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations