Primary amoebic meningoencephalitis:

Carter, S. A.

doi:10.1080/00207237808709782

International Journal of Environmental Studies

1978

DOI: 10.1080/00207237808709782

|View full text |Cite

Primary amoebic meningoencephalitis:

S. A. Carter

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1981

2014

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 8 publications

(1 citation statement)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They most often involve children in good health or young adults (i) who had been swimming in heated pools or thermal waters (Czech Republic, Belgium, or New Zealand [7,8,29,30,36]) or in ponds, lakes, or rivers (North America [1,10,17,19,21]), or (ii) who were infected as a result of using domestic water colonized by these amoebae (Australia [4,5]). …”

mentioning

confidence: 99%

Assessing the Risk of Primary Amoebic Meningoencephalitis from Swimming in the Presence of EnvironmentalNaegleria fowleri

Cabanes¹,

Wallet²,

Pringuez³

et al. 2001

Appl Environ Microbiol

View full text Add to dashboard Cite

Free-living Naegleria fowleri amoebae cause primary amoebic meningoencephalitis (PAM). Because of the apparent conflict between their ubiquity and the rarity of cases observed, we sought to develop a model characterizing the risk of PAM after swimming as a function of the concentration of N. fowleri. The probability of death from PAM as a function of the number of amoebae inhaled is modeled according to results obtained from animals infected with amoeba strains. The calculation of the probability of inhaling one or more amoebae while swimming is based on a double hypothesis: that the distribution of amoebae in the water follows a Poisson distribution and that the mean quantity of water inhaled while swimming is 10 ml. The risk of PAM for a given concentration of amoebae is then obtained by summing the following products: the probability of inhaling n amoebae ؋ the probability of PAM associated with inhaling these n amoebae. We chose the lognormal model to assess the risk of PAM because it yielded the best analysis of the studentized residuals. Nonetheless, the levels of risk thereby obtained cannot be applied to humans without correction, because they are substantially greater than those indicated by available epidemiologic data. The curve was thus adjusted by a factor calculated with the least-squares method. This provides the PAM risk in humans as a function of the N. fowleri concentration in the river. For example, the risk is 8.5 ؋ 10 ؊8 at a concentration of 10 N. fowleri amoebae per liter.

show abstract

mentioning

confidence: 99%

Assessing the Risk of Primary Amoebic Meningoencephalitis from Swimming in the Presence of EnvironmentalNaegleria fowleri

Cabanes¹,

Wallet²,

Pringuez³

et al. 2001

Appl Environ Microbiol

View full text Add to dashboard Cite

show abstract

Effect of exogenous iron on the viability of pathogenicNaegleria fowleri in serum

Newsome

Wilhelm

1981

Experientia

View full text Add to dashboard Cite

When Naegleria fowleri (Lee) was incubated in newborn calf and human serum an amebicidal effect was observed. Heat inactivation of both sera resulted in the recovery of viable amebae after incubation in these sera. Exogenous iron added to non-heat inactivated calf serum improved viability slightly but was without effect when added to human serum not heat inactivated. Exogenous iron greatly enhanced growth and/or viability in heat inactivated calf serum. Viability of amebae also was considerably enhanced in human serum which was heat inactivated when pH was lowered in conjunction with iron supplements.

show abstract

Soil is the origin for the presence of Naegleria fowleri in the thermal recreational waters

et al. 2014

View full text Add to dashboard Cite

Naegleria fowleri is found in most geothermal baths of Guadeloupe and has been responsible for the death of a 9-year-old boy who swam in one of these baths in 2008. We wanted to determine the origin for the presence of this amoeba in the water. Water samples were taken at the origin of the geothermal sources and at the arrival in the baths. After filtration, cultures were made and the number of Naegleria present was determined using the most probable number method. Soil samples collected in the proximity of the baths were also tested for the presence of thermophilic amoebae. The species identification was obtained by PCR. During three consecutive months, no Naegleria could be found at the origin of any geothermal source tested. In contrast, N. fowleri was isolated at least once in all baths at the arrival of the water, except one. Thermophilic amoebae could be found in each soil sample, especially near the baths located at a lower altitude, but N. fowleri was only isolated near two baths, which were also the baths most often contaminated with this species. So it appears that the contamination of the water with N. fowleri occurs after emerging from the geothermal source when the water runs over the soil. Therefore, it should be possible to reduce the concentration of N. fowleri in the geothermal baths of Guadeloupe to for example less than 1 N. fowleri/10 L by installing a pipeline between the geothermal sources and the baths and by preventing flooding water from entering the baths after rainfall. By taking these measures, we were able to eliminate N. fowleri from a pool located inside a reeducation clinic.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Primary amoebic meningoencephalitis:

Cited by 8 publications

References 21 publications

Assessing the Risk of Primary Amoebic Meningoencephalitis from Swimming in the Presence of EnvironmentalNaegleria fowleri

Assessing the Risk of Primary Amoebic Meningoencephalitis from Swimming in the Presence of EnvironmentalNaegleria fowleri

Effect of exogenous iron on the viability of pathogenicNaegleria fowleri in serum

Soil is the origin for the presence of Naegleria fowleri in the thermal recreational waters

Contact Info

Product

Resources

About