Primary argon laser trabeculoplasty vs. pilocarpine Short‐term effects

Bergeå, Bengt; Svedbergh, Björn

doi:10.1111/j.1755-3768.1992.tb02114.x

Cited by 15 publications

(5 citation statements)

References 45 publications

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“…Based on the Goldmann's equation, the amount of IOP reduction was not fully explained by TOF improvement. This finding is congruent with other similar studies [22][23][24].…”

Section: Discussionsupporting

confidence: 94%

Predictors of selective laser trabeculoplasty success in open angle glaucoma or ocular hypertension: does baseline tonography have a predictive role?

et al. 2020

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BackgroundThe determinants of success of selective laser trabeculoplasty (SLT) in treatment-naïve patients with open angle glaucoma (OAG) and ocular hypertension (OHT) have not been understood fully. Therefore, we have conducted this study to explore the predictors of success.MethodsThis is a retrospective review of a pre-existing database of patients who had received primary SLT at St Thomas’ Hospital, London, UK. Patients with OAG and OHT who had received primary 360° SLT treatment and had reliable baseline tonographic outflow facility (TOF) with minimum of 1 year of follow-up were included. Univariate and multivariate analyses were performed to find the determinants of success.ResultsOne hundred and seventy-four patients between August 2006 and February 2010 had received primary 360° SLT treatment and had baseline TOF measurement. Of these, 72 subjects fulfilled the eligibility criteria. In multivariate regression analysis, the only variable associated with success was baseline intraocular pressure (IOP) (R2=0.32, beta=−0.51, p<0.001, 95% CI −2.02 to −0.74).ConclusionTo our knowledge, this is the only study investigating the pretreatment TOF (measured with electronic Shiøtz tonography) and IOP as determinants of success 12 month’s post-360° SLT in treatment-naïve patients with OAG and OHT. This study demonstrated that pretreatment IOP (and not TOF) is the only determinant of success after primary SLT therapy.

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“…Based on the Goldmann's equation, the amount of IOP reduction was not fully explained by TOF improvement. This finding is congruent with other similar studies [22][23][24].…”

Section: Discussionsupporting

confidence: 94%

Predictors of selective laser trabeculoplasty success in open angle glaucoma or ocular hypertension: does baseline tonography have a predictive role?

et al. 2020

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“…Our results differ significantly from these ALT studies, in that although a comparable level of IOP reduction was achieved, the tonographic outflow facility increase following SLT was only about half of that observed with ALT 14–16 18. This is a curious finding which could indicate a difference in mechanism of action of SLT as compared to ALT.…”

Section: Discussioncontrasting

confidence: 99%

“…Most studies on the effect of ALT on outflow facility were done in patients who were already on medical treatment making a direct comparison difficult 12–17. The only study of the effect of ALT on outflow facility in medically untreated eyes with POAG was performed over 15 years ago by Bergeå et al 18 A comparable level of IOP reduction was found in those with POAG but this reduction was associated with a much higher tonographic outflow facility increase (65%). Although Bergeå's study used the same measurement technique, the results are limited by the relatively small number of POAG patients.…”

Section: Discussionmentioning

confidence: 97%

Effect of primary selective laser trabeculoplasty on tonographic outflow facility: a randomised clinical trial

Goyal

Beltran‐Agullo

Rashid

et al. 2010

British Journal of Ophthalmology

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“…Immediate IOP changes after ALT in this study have already been reported (BergeP 8c Svedbergh 1992).…”

mentioning

confidence: 53%

Primary argon laser trabeculoplasty vs pilocarpine II: Long‐term effects on intraocular pressure and facility of outflow

Bergeå

Bodin

Svedbergh

1994

Acta Ophthalmologica

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In a prospective study 82 patients recently diagnosed with simple or capsular glaucoma were randomized to receive primary argon laser trabeculoplasty or pilocarpine treatment. A 2-year follow-up showed a better success rate in the laser group, with less need for additional therapy. The average intraocular pressure and peak pressure was lower and the daytime pressure variation was significantly less in the laser group. The better increase in facility of outflow in the laser group was not statistically significant. In capsular glaucoma, laser treatment resulted in a significantly lower average pressure than with medication. In simple glaucoma the effect was about the same in the two treatment groups. Increase in facility of outflow was significantly better in simple glaucoma than in capsular glaucoma. High initial intraocular pressure gave a significantly lower success rate. Primary argon laser trabeculoplasty as a single glaucoma treatment seems advantageous in comparison to medication with pilocarpine for regulating intraocular pressure.

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Primary argon laser trabeculoplasty vs. pilocarpine Short‐term effects

Cited by 15 publications

References 45 publications

Predictors of selective laser trabeculoplasty success in open angle glaucoma or ocular hypertension: does baseline tonography have a predictive role?

Predictors of selective laser trabeculoplasty success in open angle glaucoma or ocular hypertension: does baseline tonography have a predictive role?

Effect of primary selective laser trabeculoplasty on tonographic outflow facility: a randomised clinical trial

Primary argon laser trabeculoplasty vs pilocarpine II: Long‐term effects on intraocular pressure and facility of outflow

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