Primary brain abscess with Nocardia farcinica in an immunocompetent patient

A case of systemic nocardiosis in systemic vasculitis and a review of the literature

“…(16) Although our patient was asymptomatic, the MR imaging findings were consistent with characteristics that have been noted in past studies. (17,18) This leads to the dilemma of whether patients undergoing immunosuppressive therapy should be screened early for nocardiosis, especially if they present with nonspecific symptoms.…”

Nocardia in Solid Organ Transplant Recipients

“…Organisms appear in tissue sections as gram-positive branching and beading rods surrounded by a pyogenic inflammatory reaction (2,38). No (14,31,(44)(45)(46). (76,77) and been effective in human cases (14,78 (1,2,11,15,36,44,(47)(48)(49)(50)(51)(52)(53)(54)(55)(56)59,(61)(62)(63)(65)(66)(67)(68)(69)(70)(71)(72)(73)(74)(75) …”

“…There are increasing reports of successful outcomes with the use of meropenem in the treatment of Nocardia, generally in combination with other agents and especially for treatment of brain abscesses (34,44,66,79,80). Susceptibility studies suggest meropenem is less active against the more common N. asteroides complex organisms than imipenem; however, it is more active against N. brasiliensis and N. otitidiscaviarum (74).…”

Nocardia osteomyelitis in an immunosuppressed patient

“…The data of nocardiosis is limited in the literature and is usually presented as isolated case reports undermining its significance in human infections 13,14 . It has been noted that a delay in diagnosis among immunosuppresed patients infected with nocardia may be responsible for treatment failure and poor prognosis 15,16 .…”