Primary Cardiac T Cell Lymphoma Mimicking ST-Elevation Myocardial Infarction

Pirzada, Ashar; Connors, Sean P.; Harris, Scott L.; Adams, Corey

doi:10.1159/000479676

Cited by 4 publications

(1 citation statement)

References 9 publications

(15 reference statements)

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“…Histologically, nearly all cases of PCL are of B-cell origin, with diffuse large B-cell lymphoma being the most common subtype [1,2] . Conversely, we report an extremely rare PCL subtype of T-cell origin, described in only a handful of case reports over the last two decades [3][4][5][6] . In the largest literature review concerning PCL, only 5 of 197 cases were of T-cell origin [1] .…”

Section: Discussionmentioning

confidence: 83%

Diagnosis of Primary Cardiac T-cell Lymphoma: Feasibility and Safety of Endomyocardial Biopsy Guided by Pre-acquired Cardiovascular Magnetic Resonance

Avella

Giordano

Buffa

et al. 2021

European Journal of Case Reports in Internal Medicine

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Background: Multimodality imaging of a cardiac mass lesion may raise suspicion of a primitive cardiac lymphoma (PCL). However, a definitive diagnosis requires histopathological confirmation. Methods: This report describes the methodology we used to perform biopsy sampling of a cardiac mass lesion affecting a 45-year-old man. In order to increase endomyocardial biopsy diagnostic accuracy, we used pre-acquired cardiac magnetic resonance (CMR) images to guide the bioptome on a cardiac site overtly infiltrated by the suspected tumour. The right ventricular outflow tract was identified as the target site for biopsy sampling. To reduce the risk of the procedure, the biopsy was performed at a safe distance from the tip of a diagnostic quadripolar catheter positioned at the level of the pulmonary valve, previously identified by pacing manoeuvres. The reported approach demonstrated safety and diagnostic accuracy, allowing the identification of an extremely rare PCL subtype of T-cell origin. Conclusion: Biopsy sampling of a suspected tumour may be safely and accurately performed using pre-acquired CMR images to guide the bioptome on the target site.

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