Primary Cecal Squamous Cell Carcinoma: A Case Report of a Rare Tumor with Poor Prognosis

Mohamed, Bouzroud; Azzakhmam, Mustapha; Mehdi, Aboulfeth El; Mohammed, Bouchentouf Sidi; Hakim, El Kaoui; Mohaned, Oukabli; Bourazza, Ahmed

doi:10.1155/2021/6680702

Cited by 2 publications

(2 citation statements)

References 10 publications

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“…These emergencies are more common with SCC of the colon due to the more aggressive nature of this tumor. Only two cases of cecal perforation in primary cecal SCC have been found in the literature review, and our case is the third [2,10].…”

Section: Discussionmentioning

confidence: 82%

Primary Squamous Cell Carcinoma of the Cecum: A Case Report

Albandar,

Aljarayhi

2024

Cureus

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Primary squamous cell carcinoma (SCC) of the colon is an exceptionally rare diagnosis. The etiology and pathogenesis of this entity remain unclear. It usually presents in patients as an emergency, typically with the tumor in the advanced stage. We report a case of SCC of the cecum presenting with perforation, initially diagnosed as SCC of unknown origin. The patient underwent a limited right hemicolectomy and end ileostomy outside our center. The patient was referred to us for further workup and possible adjuvant chemotherapy. She was assessed clinically and found to have had poor appetite and anorexia for a month, with an intermittent fever documented at 39 degrees. Thus, the patient was elected to get admitted for a septic workup and re-staging by CT scan and tumor biomarkers. CT showed a phlegmon and abscess formation at the right iliac fossa that was attached to surrounding structures, including the abdominal wall. Drain placement at the site of the phlegmon was attempted but failed due to bowel overlapping. Therefore, the patient was booked for surgical exploration and drainage, where all structures were resected en bloc. Histopathological examination revealed well-differentiated keratinized SCC with lymph node metastasis. The diagnosis of primary SCC of the cecum was confirmed after investigations to rule out primary sources were negative. Surgical resection remains the mainstay of management, with a possible role for chemotherapy and radiation therapy. The prognosis in these cases is usually poor. This warrants early diagnosis and management. Studies are needed to establish a management protocol for this entity.

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Section: Discussionmentioning

confidence: 82%

Primary Squamous Cell Carcinoma of the Cecum: A Case Report

Albandar,

Aljarayhi

2024

Cureus

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“…Clinically, colorectal SCC symptoms are practically identical to those of colorectal adenocarcinoma, including gastrointestinal bleeding, abdominal pain, weight loss, anorexia, constipation, and diarrhea [ 12 ]. However, colorectal SCC can be discovered with some complications such as acute abdominal and intestinal obstruction in our case.…”

Section: Discussionmentioning

confidence: 99%

Primary Squamous Cell Carcinoma of the Sigmoid Revealed by Acute Intestinal Occlusion in Moroccan Young Male Patient: A Case Report and Literature Review

Haouane¹,

Badr²,

Kaakoua³

et al. 2023

Cureus

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Primary colorectal squamous cell carcinoma (SCC) is an extremely rare subtype of colon cancer, with an incidence of less than 1% of colorectal malignancies. We report a case of a 40-year-old male patient admitted to the emergency department with symptoms of acute intestinal obstruction. Histopathological evaluation of colonoscopic biopsies revealed squamous cell carcinoma. A sigmoidectomy was performed.In order to enrich the medical literature, we add our case to the collection of colorectal squamous cell carcinoma cases by analyzing and summarizing the clinical, pathological, and therapeutic features of this rare entity.

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Primary Cecal Squamous Cell Carcinoma: A Case Report of a Rare Tumor with Poor Prognosis

Cited by 2 publications

References 10 publications

Primary Squamous Cell Carcinoma of the Cecum: A Case Report

Primary Squamous Cell Carcinoma of the Cecum: A Case Report

Primary Squamous Cell Carcinoma of the Sigmoid Revealed by Acute Intestinal Occlusion in Moroccan Young Male Patient: A Case Report and Literature Review

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