Primary extensive pyomyositis in an immunocompetent patient: case report and literature review

Al-Najar, Mahasen; Obeidat, Firas; Ajlouni, Jihad; Mithqal, Ayman; Hadidy, Azmy M.

doi:10.1007/s10067-010-1569-1

Cited by 14 publications

(13 citation statements)

References 12 publications

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“…Pyomyositis, previously rare in the west, is now occasionally seen in AIDS patients. Other bacteria, such as Borrelia burgdorferi (Lyme disease) and Legionella pneumophila (Legionnaires’ disease) may infrequently cause myositis (Crum-Cianflone, 2008; Al-Najar et al, 2010; Kung et al, 2011). …”

Section: Step 1: Overview and Understanding Of Myopathies In Systemicmentioning

confidence: 99%

“…Sporotrichosis and histoplasmosis can involve a single muscle or a group of muscles with abscess formation. Patients with disseminated candidiasis can develop papular rash, myalgia, and diffuse muscle weakness (Al-Najar et al, 2010). …”

Section: Step 1: Overview and Understanding Of Myopathies In Systemicmentioning

confidence: 99%

“…Trichinosis on occasion may mimic mild dermatomyositis and may require muscle biopsy. Generally bacterial and fungal infections have other associated local and systemic symptoms that patients rarely need a muscle biopsy for the diagnosis (Al-Najar et al, 2010; Kung et al, 2011). …”

Section: Step 3: Utility Of Laboratory Testing Including Muscle Biopsymentioning

confidence: 99%

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Stepwise Approach to Myopathy in Systemic Disease

Chawla¹

2011

Front. Neur.

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Muscle diseases can constitute a large variety of both acquired and hereditary disorders. Myopathies in systemic disease results from several different disease processes including endocrine, inflammatory, paraneoplastic, infectious, drug- and toxin-induced, critical illness myopathy, metabolic, and myopathies with other systemic disorders. Patients with systemic myopathies often present acutely or sub acutely. On the other hand, familial myopathies or dystrophies generally present in a chronic fashion with exceptions of metabolic myopathies where symptoms on occasion can be precipitated acutely. Most of the inflammatory myopathies can have a chance association with malignant lesions; the incidence appears to be specifically increased only in patients with dermatomyositis. In dealing with myopathies associated with systemic illnesses, the focus will be on the acquired causes. Management is beyond the scope of this chapter. Prognosis is based upon the underlying cause and, most of the time, carries a good prognosis. In order to approach a patient with suspected myopathy from systemic disease, a stepwise approach is utilized.

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Section: Step 1: Overview and Understanding Of Myopathies In Systemicmentioning

confidence: 99%

Section: Step 1: Overview and Understanding Of Myopathies In Systemicmentioning

confidence: 99%

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Stepwise Approach to Myopathy in Systemic Disease

Chawla¹

2011

Front. Neur.

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“…4-B). It is known that elevated serum levels of CK have value in predicting the HO,6 and in anticipating a more severe state of HO7 Therefore, CK level could be a more sensitive marker to diagnose early HO than ALP level.…”

Section: Discussionmentioning

confidence: 99%

“…The clinical findings were characterized by pain in the hip and features of systemic infection. Lab findings which reveal an elevated ESR, CRP and leukocytosis can be seen in both conditions 6. Nonetheless, we need to pay attention to a number of distinguishing features.…”

Section: Discussionmentioning

confidence: 99%

Early Presentation of Heterotopic Ossification Mimicking Pyomyositis - Two Case Reports -

et al. 2012

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Early diagnosis and treatment of heterotopic ossification (HO) is essential to the prevention of complications. It is difficult to diagnose HO in its initial phase because non-specific clinical manifestations, laboratory findings and imaging findings of immature HO may mimic other diseases such as cellulitis, osteomyelitis, thrombophlebitis, deep vein thrombosis and local infection with abscess. We experienced two cases of HO, which were misdiagnosed as pyomyositis at first by clinical signs and MRI findings indicating the deep infection; the extensive intramuscular ossification appeared later on. We observed an increase of C-reactive protein and creatine kinase followed by the elevation of alkaline phosphatase with abnormal triphasic bone scan. The trajectory of these biomarkers was analyzed to get more insight into the early stages of HO along with the imaging findings. Although our cases cannot be generalized as typical of immature HO, they clearly demonstrate that the change of specific biomarkers with a careful history taking and physical examination should be noted to detect HO as early as possible while avoiding confusion with other mimicking conditions.

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Muscle Disorders Associated with Infections

Chimelli

Taratuto

2013

Muscle Disease

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Primary extensive pyomyositis in an immunocompetent patient: case report and literature review

Cited by 14 publications

References 12 publications

Stepwise Approach to Myopathy in Systemic Disease

Stepwise Approach to Myopathy in Systemic Disease

Early Presentation of Heterotopic Ossification Mimicking Pyomyositis - Two Case Reports -

Muscle Disorders Associated with Infections

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