Primary Gastric Lymphoma with Spontaneous Perforation: Report of a Case

Abstract

Primary gastric lymphoma with spontaneous perforation is rare. We report herein the case of a 53-year-old-man who was admitted to our hospital with severe epigastralgia. Emergency endoscopic examination showed a perforated gastric tumor in the lower body of the greater curvature, and a distal subtotal gastrectomy with lymph node dissection was performed. The resected tumor measured 10.0 x 8.0 cm and was associated with an area of ulceration, 8.0 x 6.0 cm in size, and perforation, 1.0 x 0.5 cm in size. Pathological examination confirmed a diagnosis of B-cell malignant lymphoma of the diffuse, medium-sized cell type. According to the Ann Arbor and Naqvi classifications, the lymphoma was stage II and stage III, respectively. Postoperative adjuvant chemotherapy comprising cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) was given. The patient is currently well with no signs of recurrence, 2 years 4 months after his operation.

Pancreaticoduodenectomy for Perforated Gastric Malignant Lymphoma: Report of a Case

“…In Japan, only one case of gastric lymphoma with a spontaneous perforation has so far been reported. 12 In the present case, a perforation occurred due to the progression of lymphoma, and we therefore chose PD to avoid any gastroduodenal complications during chemotherapy. In our case, extensive lymph node swelling was noted in the abdomen, including the para-aortic lymph node, and invasion to the pancreatic head and second portion of duodenum was thus suspected.…”

Non Hodgkin's Lymphoma of Stomach With Spontaneous Perforation: A Case Report With Review of Literature

“…Patient can be subjected to adjuvant chemotherapy on receiving the tissue diagnosis of lymphoma after getting over the problem of critical abdominal sepsis. A case of gastric lymphoma with spontaneous perforation with peritonitis has been reported in the literature in which preoperative diagnosis of lymphoma was done 11 . They did an endoscopic examination of the stomach which revealed a perforated gastric tumor in the lower part of body on the greater curvature.…”

Urgent Multivisceral Resection due to Perforated Primary Gastric Lymphoma

“…Perforation of the stomach is a common complication of peptic ulcer disease, however it is rarely associated with gastric malignancy [1]. Primary gastric lymphoma is rare, accounting for only 1%-5% of all gastric tumors [2].…”