Primary hepatic marginal B cell lymphoma of mucosa-associated lymphoid tissue (MALT) and non-alcoholic steatohepatitis (NASH): more than a coincidence?

Haefliger, Simon; Milowich, Dina; Sciarra, Amedeo; Trimeche, M; Bouilly, Justine; Kaiser, Jeff; Volpi, Stefano; Jp, Brouland; Sempoux, Christine; Leval, Laurence de

doi:10.1007/s00277-018-3565-5

Cited by 14 publications

(16 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To the best of our knowledge, 113 cases of primary hepatic MALT lymphoma have been reported in 71 articles to date, 7 – 37 of which 80 cases (including our case) had relatively detailed clinical data ( Table 1 ). Among the patients in these 113 cases, 43 patients were men (38%) and 48 were women (42%) (the sex was not indicated in the remaining cases), with an age range of 30 to 89 years and a median age of 63.5 years.…”

Section: Discussionmentioning

confidence: 93%

A case of primary hepatic extranodal marginal zone B-cell mucosa-associated lymphoid tissue (MALT) lymphoma treated by radiofrequency ablation (RFA), and a literature review

Peng

Sui

et al. 2021

J Int Med Res

View full text Add to dashboard Cite

Primary hepatic mucosa-associated lymphoid tissue (MALT) lymphoma is an extremely rare liver malignancy that usually lacks characteristic imaging findings and which is often misdiagnosed. We report a 63-year-old woman diagnosed with primary hepatic extranodal marginal zone B-cell lymphoma, MALT type. The patient underwent needle biopsy and radiofrequency ablation (RFA), and showed no signs of relapse during the 12-month postoperative follow-up. This case stresses the rarity of primary hepatic MALT-type lymphoma and the unique and effective treatment for this patient. Our patient received RFA, which showed good efficacy and which provides a new option for the treatment of hepatic MALT lymphoma. We also present our findings from a systematic review to improve the current understanding of this disease.

show abstract

Section: Discussionmentioning

confidence: 93%

A case of primary hepatic extranodal marginal zone B-cell mucosa-associated lymphoid tissue (MALT) lymphoma treated by radiofrequency ablation (RFA), and a literature review

Peng

Sui

et al. 2021

J Int Med Res

View full text Add to dashboard Cite

show abstract

“…Although the incidence of primary hepatic MALT lymphoma is extremely rare, some unique clinical characteristics were reported in the literatures (Table 1) [6][7][8][9][10][11][12][13][14][15]. Most of primary hepatic MALT lymphoma cases occurred in elderly people and were presented with incidentally detected liver masses without specific symptoms [6,7].…”

Section: Discussionmentioning

confidence: 99%

Primary hepatic extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue

Choi

Kim

et al. 2020

J Pathol Transl Med

View full text Add to dashboard Cite

Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma), is one of the specific type of low-grade B-cell lymphoma not infrequently found worldwide. It typically involves mucosal sites such as stomach and conjunctiva; however, primary hepatic MALT lymphoma has been extremely rarely reported. We describe a case of hepatic MALT lymphoma in a 70-year-old male patient who underwent left hepatectomy due to the incidentally detected liver masses at a medical checkup. The resected specimen revealed multinodular masses consisting of small-to-intermediate-sized lymphoid cells with serpentine pattern and focal lymphoepithelial lesions. The tumor cells were diffusely positive for CD20 and Bcl-2 but negative for CD3, CD10, CD5, CD23, CD43, and cy-clinD1. The Ki-67 labeling index was 10% and immunoglobulin heavy chain gene rearrangement study confirmed monoclonal proliferation. In this paper, we discuss several unique clinicopathologic characteristics which will be helpful to the differential diagnosis of hepatic MALT lymphoma.

show abstract

“…12 Some scholars believe the continuous in ammatory stimulation may induce the occurrence of the disease. 5 In previous case reports, primary hepatic MALT lymphoma was considered to be related to primary biliary cirrhosis (PBC), 54 HCV, 19,72,76,77 HBV, 48,62 HP infection, 31 and non-alcoholic steatohepatitis (NASH), 27 etc. Meanwhile, some literatures indicated that it might be related to Epstein-Barr virus, which induced polyclonal B-cell proliferation to lead to lymphoma.…”

Section: Discussionmentioning

confidence: 99%

A Case of Primary Hepatic Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue (MALT) type Treated by Radiofrequency Ablation (RFA) and Literature Review.

Xu¹,

Peng²,

Sui³

et al. 2020

Preprint

View full text Add to dashboard Cite

BackgroundPrimary hepatic mucosa-associated lymphoid tissue (MALT) lymphoma is an extremely rare liver malignancy and is usually lack characteristic imaging findings, which is often misdiagnosed. Case presentationThe present study reports a case of a 63-year-old woman diagnosed with primary hepatic extranodal marginal zone B-cell lymphoma of MALT type. The patient received the needle biopsy and radiofrequency ablation and has not shown relapse up for the following 12 months.ConclusionsThis case is reported for its rarity and the treatment for this patient is unique and effective. Our case provides a new option for the treatment of hepatic MALT lymphoma. We also present our findings from a systematic review to improve our current understanding of the disease.

show abstract

Primary hepatic marginal B cell lymphoma of mucosa-associated lymphoid tissue (MALT) and non-alcoholic steatohepatitis (NASH): more than a coincidence?

Cited by 14 publications

References 15 publications

A case of primary hepatic extranodal marginal zone B-cell mucosa-associated lymphoid tissue (MALT) lymphoma treated by radiofrequency ablation (RFA), and a literature review

A case of primary hepatic extranodal marginal zone B-cell mucosa-associated lymphoid tissue (MALT) lymphoma treated by radiofrequency ablation (RFA), and a literature review

Primary hepatic extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue

A Case of Primary Hepatic Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue (MALT) type Treated by Radiofrequency Ablation (RFA) and Literature Review.

Contact Info

Product

Resources

About