Primary male urethral squamous cell carcinoma presenting with a genital abscess

Abstract

Abbreviations & Acronyms BSC = best supportive care Cx = chemotherapy nd = not described Rx = radiation therapy Correspondence: Hiroya

Non-mucinous adenocarcinomas and squamous cell carcinomas of the anal region masquerading as abscess or fistula: a retrospective analysis and systematic review of literature

“…The authors reported each 1 case of SCC associated with abscess or fistula (Chandramohan et al 2010 ; Jamieson and Goode 1982 ; Seya et al 2007 ; Moore et al 2016 ; Creta et al 2017 ; Garg et al 2018 ; Mizusawa et al 2019 ). In the majority of the cases, the patients were male (5/7), only 1 was female, and in 1 case, the sex was not reported.…”

“…In one patient, the abscess was located in the gluteal region (Chandramohan et al 2010 ). In the remaining 4 case reports, the infection was found in the perineal region followed by the delayed diagnosis of a urethral tumour (3 cases) (Moore et al 2016 ; Garg et al 2018 ; Mizusawa et al 2019 ) or a carcinoma of unknown primary origin (CUP) (Creta et al 2017 ) (delay of 2–18 months).…”

“…For instance, Jamieson et al ( 1982 ) performed an isotopic bone and a CT scan only after the third recurrence of the tumour; Seya et al ( 2007 ), Chandramohan et al ( 2010 ) and Creta et al ( 2017 ) carried out endoscopic examination prior to the operation. Furthermore, Chandramohan et al ( 2010 ), Moore et al ( 2016 ), Creta et al ( 2017 ), Garg et al ( 2018 ) and Mizusawa et al ( 2019 ) completed the staging with a cross-sectional imaging.…”

“…No further surgery was done for the patient in Chandramohan et als ( 2010 ) case report. Due to the delayed diagnosis of malignancy in the patients with urethral tumour and CUP, an extended resection was necessary (Moore et al 2016 ; Creta et al 2017 ; Garg et al 2018 ; Mizusawa et al 2019 ). However, only two patients were eligible for surgery (Moore et al 2016 ; Mizusawa et al 2019 ), one was in a poor general condition and therefore not suitable for en bloc tumour resection (Creta et al 2017 ) and a further one refused an extended resection (Garg et al 2018 ).…”

“…For two patients, the outcome was not mentioned (Chandramohan et al 2010;Garg et al 2018), and one patient was lost to follow up after 3 months (Creta et al 2017). Three patients died after 17 (Mizusawa et al 2019), 18 (Jamieson and Goode 1982) and 24 (Moore et al 2016) months, respectively. The patient in Seya et al (2007) report showed a recurrence-free survival of the SCC in the anal region for 10 years.…”