Primary multifocal extranodal lymphoma of the kidneys, ovaries and bones: utility of FDG PET/CT

Lu, Shaoying; Tan, Mingjia; Osmany, Saabry

doi:10.1007/s11739-011-0697-1

Cited by 3 publications

(3 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…PET/CT scans are also used in lymphoma to guide biopsies and evaluate treatment response. [ 8 ] Ultimately, however, the confirmatory diagnosis was based on pathologic examination; endoscopic biopsy, breast biopsy, and cerebrospinal fluid cytology played a very important role in the diagnosis of DLBCL.…”

Section: Discussionmentioning

confidence: 99%

Multifocal extranodal lymphoma

Lin²,

Zhang³

et al. 2016

Medicine

View full text Add to dashboard Cite

Introduction:We report an unusual and interesting case of non-Hodgkin lymphoma involving 7 extranodal sites.In this case, a 43-year-old woman with diffuse large B-cell lymphoma, including stomach, breasts, pancreas, adrenal glands, ovary and bones, was confirmed by biopsy and positron emission tomography/computed tomography scan. The patient achieved a complete response after 2 cycles of chemotherapy with combined rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone, but subsequently developed central nervous system involvement.Conclusion:This case illustrated the usefulness of positron emission tomography/computed tomography in diagnosis, disease staging, and assessment of response to therapy. Selection of the optimal treatment regimen is challenging and needs further research.

show abstract

Section: Discussionmentioning

confidence: 99%

Multifocal extranodal lymphoma

Lin²,

Zhang³

et al. 2016

Medicine

View full text Add to dashboard Cite

show abstract

“…Hodgkin disease (HD) and non-Hodgkin lymphoma (NHL) can arise from extranodal sites which include the gastrointestinal tract, nervous tissue, bone, skin and the genitourinary tract. Primary renal lymphoma is rare but secondary renal involvement is frequent ( 92, 93 ). PET/CT can detect multifocal renal involvement or involvement of adjacent abdominal lymph nodes.…”

Section: Renal Cell Cancermentioning

confidence: 99%

Molecular Imaging of Urogenital Diseases

Cho

Szabó

2014

Seminars in Nuclear Medicine

View full text Add to dashboard Cite

There is an expanding and exciting repertoire of PET imaging radiotracers for urogenital diseases, particularly in prostate cancer, renal cell cancer, and renal function. Prostate cancer is the most commonly diagnosed cancer in men. With growing therapeutics options for the treatment of metastatic and advanced prostate cancer, improved functional imaging of prostate cancer beyond the limitations of conventional computed tomography (CT) and bone scan (BS) is becoming increasingly important for both clinical management and drug development. PET radiotracers beyond 18F-Fluorodeoxyglucose (FDG) for prostate cancer include 18F-Sodium Fluoride, 11C-Choline and 18F-Fluorocholine and 11C-Acetate. Other emerging and promising PET radiotracers include a synthetic L-leucine amino acid analog (anti-18F-FACBC), dihydrotestosterone analog (18F-FDHT) and prostate specific membrane antigen (PSMA) based PET radiotracers (ex. 18F-DCFBC, 89Zr-DFO-J591, 68Ga(HBED-CC)). Larger prospective and comparison trials of these PET radiotracers are needed to establish the role of PET/CT in prostate cancer. Renal cell cancer imaging with FDG PET/CT although available can be limited, especially for detection of the primary tumor. Improved renal cell cancer detection with carbonic anhydrase IX (CAIX) based antibody (124I-girentuximab) and radioimmunotherapy targeting with 177Lu-cG250 appear promising. Evaluation of renal injury by imaging renal perfusion and function with novel PET radiotracers include p-18F-fluorohippurate (18F-PFH) and hippurate m-cyano-p-18F-fluorohippurate (18F-CNPFH) and Rubidium-82 chloride (typically used for myocardial perfusion imaging). Renal receptor imaging of the renal renin angiotensin system with a variety of selective PET radioligands are also becoming available for clinical translation.

show abstract

“…Extranodal localization exists in 25%-40% of all NHL cases and can occur in any organ including gastrointestinal tract, head-neck, orbita, central nervous system, lungs, bones, breast, testis, thyroid and genitourinary system ( 3 ). It may be multifocal involving two or more organs ( 4 ).…”

Section: Case Reportmentioning

confidence: 99%

FDG PET-CT Finding in Bilateral Renal and Bone Involvement of Diffuse Large B-Cell Lymphoma

Tan

Yılmaz²,

Ozhan³

et al. 2014

Mirt

View full text Add to dashboard Cite

Thirty-six year old male patient with pathological fracture of the left tibia underwent intramedullary and soft tissue curettage. The histopathological examination revealed diffuse large B cell lymphoma. The patient underwent F18-FDG PET-CT scanning for initial staging. FDG PET-CT scan revealed hypermetabolic lesions at the left tibia and in bilateral kidneys. After the systemic chemotherapy and local radiotherapy to the tibia, repeated FDG PET/CT scan showed improvement of the previous hypermetabolic lesions, suggesting good response to therapy. Bone and renal involvement is an uncommon variant of diffuse large B-cell lymphoma and FDG PET-CT is an useful whole body imaging modality in these cases.

show abstract

Primary multifocal extranodal lymphoma of the kidneys, ovaries and bones: utility of FDG PET/CT

Cited by 3 publications

References 5 publications

Multifocal extranodal lymphoma

Multifocal extranodal lymphoma

Molecular Imaging of Urogenital Diseases

FDG PET-CT Finding in Bilateral Renal and Bone Involvement of Diffuse Large B-Cell Lymphoma

Contact Info

Product

Resources

About