Primary retroperitoneal mucinous cystadenoma

Abstract

HighlightsPRMCs are very rare and they share macroscopical and histological similarity to ovarian cystadenomas.It is important to rule out Echinococcosis specially in endemic regions such as South America.Complete surgical excision of the PRMCs is recommended to eliminate the risk of infection, recurrence and malignant degeneration.It is important to remember that cystic fluid spillage has to be prevented due to the uncertain pathology of the tumor in most of the cases.

First Report of Retroperitoneal Mucinous Cystadenoma in a Patient with Hirsutism

“…Furthermore, the PRMC resembles ovarian mucinous cystadenomas. 1,[5][6][7] This theory would explain why women have higher reported incidence of being diagnosed with PRMCs. 1 The second most commonly referenced theory is that these cysts arise from the invagination of the multipotential mesothelium followed by mucinous metaplasia of the mesothelial cell lining, which gives rise to the mucinous cyst.…”

“…1,[5][6][7] This theory would explain why women have higher reported incidence of being diagnosed with PRMCs. 1 The second most commonly referenced theory is that these cysts arise from the invagination of the multipotential mesothelium followed by mucinous metaplasia of the mesothelial cell lining, which gives rise to the mucinous cyst. 1,3,5,[8][9][10][11][12][13][14] Calretinin staining was weak compared to the ER stain, which stained both the mucinous cyst cells and the stroma (Figure 3).…”

“…1 The second most commonly referenced theory is that these cysts arise from the invagination of the multipotential mesothelium followed by mucinous metaplasia of the mesothelial cell lining, which gives rise to the mucinous cyst. 1,3,5,[8][9][10][11][12][13][14] Calretinin staining was weak compared to the ER stain, which stained both the mucinous cyst cells and the stroma (Figure 3). Because calretinin stains mesothelial cells, the patient's cyst does not appear to be mesothelial in origin and does not support this hypothesis.…”

“…3 Therefore, PRMC is generally diagnosed post-surgical resection. 1 Here, we present the first reported case of concurrent presentation of PRMC, elevated pre-operative levels of dehydroepiandrosterone sulfate (DHEA-S), and hirsutism in the English literature.…”

“…rimary retroperitoneal mucinous cystadenomas (PRMC) are rare neoplasms of unknown origin most commonly reported in women of childbearing age. 1 Preoperative diagnosis of benign PRMC is difficult based on radiology findings alone, 2 and limited biopsy or laboratory sampling is insufficient for definitively diagnosing PRMC. 3 Therefore, PRMC is generally diagnosed post-surgical resection.…”