Primary Surgery vs Primary Sclerotherapy for Head and Neck Lymphatic Malformations

Balakrishnan, Karthik; Menezes, Maithilee D.; Chen, Brian S.; Magit, Anthony; Perkins, Jonathan A.

doi:10.1001/jamaoto.2013.5849

Cited by 80 publications

(63 citation statements)

References 13 publications

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“…For these types, surgery should be considered rather than sclerotherapy [15]. OK-432 has been the most widely reported sclerosing agent in these cases [12,16] and has been reported to be effective in up to 96% of patients undergoing sclerotherapy for lymphatic malformation in the neck space, with a long-term response rate of 76.3% [6]. Because the therapeutic response to OK-432 usually takes about 6 weeks or more, and because the number of injections does not correlate with the success rate and surgical excision is not considered to be more difficult after OK-432 sclerotherapy, the exact timing of conversion from sclerotherapy to surgical excision should be chosen carefully [6].…”

Section: Indications For Sclerotherapymentioning

confidence: 99%

Ultrasound-guided sclerotherapy for benign non-thyroid cystic mass in the neck

Kim

2014

Ultrasonography

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Surgical excision has traditionally been the treatment of choice for benign non-thyroid cystic neck masses, including lymphatic malformation, ranula, branchial cleft cyst, thyroglossal duct cyst, and parathyroid cyst. However, there is a tendency toward recurrence after surgery, and surgery may be accompanied by complications, including nerve injuries, vascular injuries, and scar formation. Ultrasound-guided sclerotherapy using various agents has been challenged and successfully applied as an alternative treatment for benign non-thyroid cystic neck masses. This report reviews the available sclerosing agents and describes the applications of sclerotherapy to the treatment of benign cystic masses in the neck.

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Section: Indications For Sclerotherapymentioning

confidence: 99%

Ultrasound-guided sclerotherapy for benign non-thyroid cystic mass in the neck

Kim

2014

Ultrasonography

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“…Sclerotherapy, however, has demonstrated similar outcomes at 1 year, with reduced morbidity 10. Sclerotherapy is typically performed using one of a variety of sclerosing agents by instilling 50% of the volume of aspirated lymph under ultrasound guidance.…”

Section: Discussionmentioning

confidence: 99%

Doxycycline sclerotherapy for post-traumatic inguinal lymphocele in a child

Harrington¹,

Tackett

Graeber

et al. 2018

BMJ Case Reports

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Lymphoceles are abnormal collections of lymphatic fluid caused by a disruption in the lymphatic channels and leakage of lymph. This most commonly occurs after surgical procedures, but occasionally lymphoceles may be the result of trauma, more commonly penetrating trauma. Lymphoceles resulting from blunt trauma are rare in both adults and children. In the adult population, there are few published case reports, and management principles vary. To date, there are no reports of traumatic lymphoceles in the paediatric population, and therefore there is no precedent for treatment. Here, we report the case of a young boy who developed an inguinal lymphocele from a bicycle handle bar injury which was successfully treated with doxycycline sclerotherapy.

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“…Balakrishnan K et al consider primary end point of surgery should be functional optimization and symptom reduction rather than aggressive excision. [22] These author argue that patients content with surgery, with lesser or none deficits are better and further justify that residual lesions might regress overtime. However, these regressing lesions are defined with respect to presentation in childhood.…”

Section: Discussionmentioning

confidence: 99%