Primary thyroid hemangioma: a case report
and literature review

Masuom, Seyed Hossein Fattahi; Amirian-far, Azam; Rezaei, Reza

doi:10.5114/kitp.2021.109385

Cited by 4 publications

(3 citation statements)

References 24 publications

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“…In 1975, Pickleman et al. reported the initial instance of thyroid hemangioma [ 3 ]. The exact pathogenesis is poorly understood due to a limited number of reported instances.…”

Section: Discussionmentioning

confidence: 99%

“…Other reported symptoms in previous studies are neck discomfort, dysphagia, and hoarseness of voice. Other issues, such as swallowing and breathing difficulties, tracheal deviation, and paralysis of the vocal cord have been documented [ 3 , 5 , 7 ]. The duration for which these symptoms persisted varied, ranging from one month to as long as 40 years.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Sudden onset presentation of giant primary thyroid hemangioma: a rare case report

Al-Maghrabi,

Alardati,

Waggass

et al. 2024

Journal of Surgical Case Reports

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Hemangiomas are considered slow growing benign neoplasms. Primary thyroid hemangiomas are uncommon and may pose difficulty in diagnosis due to absence of distinctive imaging characteristics and related clinical symptoms. It is crucial to precisely identify these lesions to aid in implementing nonsurgical treatment plans rather than resorting to surgical procedures in certain cases. In this report we present a case of a 76-year-old female who presented with painless, rapid, and sudden notice of right-side neck swelling over a 1-day duration. Her radiological examinations raised the concern of a vascular lesion that was emoblized endovascularly. Then, it was surgically removed, which was eventually determined to be primary thyroid hemangioma. In addition, we present a literature review of previously published cases and discuss tumor pathophysiology, clinical presentations, radiology features, and differential diagnosis.

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“…In 1975, Pickleman et al. reported the initial instance of thyroid hemangioma [ 3 ]. The exact pathogenesis is poorly understood due to a limited number of reported instances.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Sudden onset presentation of giant primary thyroid hemangioma: a rare case report

Al-Maghrabi,

Alardati,

Waggass

et al. 2024

Journal of Surgical Case Reports

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show abstract

“…The occurrence of primary thyroid hemangiomas worldwide remains limited. 1) These hemangiomas are developmental anomalies due to the lack of angioblastic mesenchymal canal formation.…”

Section: Introductionmentioning

confidence: 99%

Primary Cavernous Hemangioma of the Thyroid Gland

Kim,

Lee,

Jin

et al. 2023

Int J Thyroidol

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Hemangiomas are benign vascular tumors that result from the abnormal proliferation of vascular tissue. Thyroid hemangiomas can develop as a result of procedures such as fine needle aspiration or other secondary trauma. Primary thyroid cavernous hemangioma is an extremely rare condition, with only a few reported cases. In this report, we present the case of an 83-year-old woman who complained of progressively worsening symptoms of right neck obstruction. She was undergoing levothyroxine treatment for hypothyroidism, and there was no specific family history of thyroid issues. The patient presented with a goiter and obstructive symptoms, and denied any history of trauma or invasive procedures. Thyroid sonography revealed a 6.21 cm heterogeneous dominant solid nodule in the right lobe. Additionally, a large mixed cystic and 6 cm solid mass was identified in the right lobe on CT scan. Due to the significant size of the mass and the presence of obstructive symptoms, the patient underwent a right thyroid lobectomy without further evaluations. Histologic examination of the specimen revealed a cavernous thyroid hemangioma. This case report presents our experience in diagnosing cavernous thyroid hemangioma.

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On Vascular Lesions of the Thyroid Gland with Emphasis on Intrathyroidal Hemangioma: Clinicopathologic Characterization of Two Cases and Review of the Literature

MacDonald,

Wakely,

Argyris

2024

Head and Neck Pathol

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Mesenchymal neoplasms of the thyroid gland are exceptionally rare accounting for less than 0.5% of all intrathyroidal tumors with hemangiomas comprising merely 6% of them. The clinicopathologic characteristics of two additional examples of thyroid hemangioma together with a thorough review of the pertinent literature are presented. A 62-year-old man and an 18-year-old woman presented with asymptomatic, soft-to-palpation, mobile nodules of the right thyroid lobe classified as TI-RADS 5 and TI-RADS 4, respectively, on ultrasound imaging. Microscopically, lesions featured a circumscribed, unencapsulated, lobular proliferation of variably-sized, congested, vascular channels lined by a single layer of flattened, cytologically bland endothelial cells, together with interspersed residual follicles. Vascular endothelial cells were strongly positive for CD31, CD34 and ERG, and negative for pancytokeratin AE1/AE3, TTF1, and PAX8. A diagnosis of cavernous hemangioma was rendered in the clinical setting of Hashimoto thyroiditis and follicular adenoma, respectively. Following inclusion of the current cases, a total of 53 intrathyroidal hemangiomas were identified in the literature with a patient mean age of 48.9 years (range = 0.17-84) and a slight female predilection (F:M = 1.4:1). A proclivity for the right thyroid lobe (59.6%) was noted with the striking majority of cases exhibiting features of cavernous hemangioma (95.2%). Prognosis is favorable and surgical resection is considered curative. The occasionally alarming clinical presentation in conjunction with absence of pathognomonic imaging features and limited diagnostic accuracy of FNA cytopathology for such lesions renders surgical intervention necessary for definitive diagnosis of intrathyroidal hemangiomas and exclusion of other epithelial and non-epithelial pathologic entities.

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Primary thyroid hemangioma: a case report and literature review

Cited by 4 publications

References 24 publications

Sudden onset presentation of giant primary thyroid hemangioma: a rare case report

Sudden onset presentation of giant primary thyroid hemangioma: a rare case report

Primary Cavernous Hemangioma of the Thyroid Gland

On Vascular Lesions of the Thyroid Gland with Emphasis on Intrathyroidal Hemangioma: Clinicopathologic Characterization of Two Cases and Review of the Literature

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