Principal component analysis for the protein amide I region of Raman imaging data before/after straight perm of human grey hair

Abstract

For straight perm, the microscopic mechanism is still unclear, especially for changes in the secondary structure of the protein of the hair. Expecting to find a better condition for the straight perm treatment, we made the research on grey hair using the Raman imaging technique and principal component analysis (PCA). We succeeded to detect changes in different secondary structures such as β-turn and α-helix and to visualize their distributions.