Chem. Commun.
 2024
DOI: 10.1039/d4cc03106g
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Probing the binding and antiparasitic efficacy of azobenzene G-quadruplex ligands to investigate G4 ligand design

Javier Ramos-Soriano,
Maisie Holbrow-Wilshaw,
Eliza Hunt
et al.

Abstract: Novel strategies against parasitic infections are of great importance. Here we describe a G4 DNA ligand with subnanomolar antiparasitic activity against T. brucei and a remarkable selectivity index (IC50 MRC-5/T....

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