Probiotics and Cancer: Boosting the Immune System

Upadhaya, Prashant; Kharkar, Prachi; Patil, Abhinandan; Pawar, S.H.; Disouza, John; Patravale, Vandana

doi:10.1007/978-981-15-8214-1_3

Cited by 4 publications

(3 citation statements)

References 104 publications

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“…But the most concerning part is its short shelf life, as the formulation will prepare to deteriorate by a change in temperature and various storage conditions [ 4 , 27 – 32 ]. Many studies revealed that the colony-forming unit (CFU) per gram value above 10 8 counts is found to show the health benefits [ 5 – 10 , 33 ]. But it is found that, during the storage condition, the CFU level falls below the threshold, resulting in zero pharmacological activities [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Encapsulation of Lactic Acid Bacteria by Lyophilisation with Its Effects on Viability and Adhesion Properties

Patil

Neha²,

Patwekar

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Lactobacillus (LAB) genera are considered important functional food but are found to have a short shelf life. In this study, two LAB, Lactobacillus plantarum (Lp) and Lactobacillus rhamnosus (Lr), were isolated from sheep’s milk, and whole-genome sequencing was carried out by using 16s rRNA Illumina Nextseq, the Netherlands. The LAB were encapsulated by the lyophilisation technique using different lyoprotective pharmaceutical excipients. This process was carried out using a freeze dryer (U-TECH, Star Scientific Instruments, India). Shelf-life determination was carried out by a 12-month study using the viability survival factor (Vsf). The in vitro cell adhesion technique was carried out by using the red snapper fish along with autoaggregation and cell surface hydrophobicity as vital probiotic properties. It was observed that Lp has a significantly higher (P < 0.001) Vsf of 7.2, while Lr has a Vsf of 7 (P < 0.05) when both are encapsulated with 10% maltodextrin + 5% sucrose kept at 4°C for 12 months. The result demonstrated that Lp had significantly high (P < 0.05) cell adhesion, 96% ± 1.2 autoaggregation, and 6% cell surface hydrophobicity as compared to Lr. Moreover, this study demonstrated that lyophilised LAB with lyoprotective excipients enhances shelf life without any changes in probiotic properties when kept at 4°C exhibiting all its probiotic properties.

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Section: Introductionmentioning

confidence: 99%

Encapsulation of Lactic Acid Bacteria by Lyophilisation with Its Effects on Viability and Adhesion Properties

Patil

Neha²,

Patwekar

et al. 2022

Evidence-Based Complementary and Alternative Medicine

Self Cite

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“…B and T lymphocytes make up the adaptive immune response, which is related to antigens and antibodies. At the same time, the innate immune system arises when a person is born, which responds to familiar structures called pathogen-associated molecular originals shared by most pathogens [ 32 , 33 ]. The immune system’s integrity is closely related to gut health.…”

Section: Probiotics and Immune Systemmentioning

confidence: 99%

Probiotic Supplements: Their Strategies in the Therapeutic and Prophylactic of Human Life-Threatening Diseases

Youssef

Ahmed

Zongo

et al. 2021

IJMS

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Chronic diseases and viral infections have threatened human life over the ages and constitute the main reason for increasing death globally. The rising burden of these diseases extends to negatively affecting the economy and trading globally, as well as daily life, which requires inexpensive, novel, and safe therapeutics. Therefore, scientists have paid close attention to probiotics as safe remedies to combat these morbidities owing to their health benefits and biotherapeutic effects. Probiotics have been broadly adopted as functional foods, nutraceuticals, and food supplements to improve human health and prevent some morbidity. Intriguingly, recent research indicates that probiotics are a promising solution for treating and prophylactic against certain dangerous diseases. Probiotics could also be associated with their essential role in animating the immune system to fight COVID-19 infection. This comprehensive review concentrates on the newest literature on probiotics and their metabolism in treating life-threatening diseases, including immune disorders, pathogens, inflammatory and allergic diseases, cancer, cardiovascular disease, gastrointestinal dysfunctions, and COVID-19 infection. The recent information in this report will particularly furnish a platform for emerging novel probiotics-based therapeutics as cheap and safe, encouraging researchers and stakeholders to develop innovative treatments based on probiotics to prevent and treat chronic and viral diseases.

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“…Co-aggregation facilitates specific environmental conditions that interfere with pathogenic colonization by producing certain inhibitory chemical compounds and blocks binding sites. In contrast, the auto-aggregation mechanism restrains the adherence of pathogens to vaginal epithelial cells and relieves the state of hyperplasia and vaginal tears, thereby restricting the risks of appearance of any other disorders [12,16]. Furthermore, previous studies had reported that supernatants of different Lactobacillus species can generate biosurfactants (e.g.…”

Section: Probiotic Oral and Vaginal Intercalation With The Women's Healthmentioning

confidence: 99%

Adjuvant and Beneficial Probiotic Therapy for Women Health

Balta

Butucel

Mohylyuk

2021

Roum Arch Microbiol Immunol

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Probiotics are living microbial strains, also considered functional foods, that improve the human intestine and mucosal sites' functionality and normalize the immune system balance. This symbiosis between the human body and microorganisms has attracted scientists and showed a notable role in maintaining human health. The microbiota composition within different sites of the organs can change rapidly and unfavorably, leading to the development of infections or abnormal conditions. The treatments with antibiotics affect and disturb the overall normal microflora, and specifically to the vaginal tract, by inhibiting the spread of the normal microflora of Lactobacillus species. In this sense, probiotics have shown to be an integrative and complementary therapy for the amelioration and prevention of vaginal infections in women. The main objective of the current review is to highlight the importance of probiotics to prevent and treat antibiotic-associated acute and chronic diseases and highlight their possible beneficial impact on women reproductive health. Moreover, the review discusses the recent clinical findings of probiotic therapy concerning protection against vaginal diseases, well-being, infant development, and human body detoxification from the chemical compounds.

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Probiotics and Cancer: Boosting the Immune System

Cited by 4 publications

References 104 publications

Encapsulation of Lactic Acid Bacteria by Lyophilisation with Its Effects on Viability and Adhesion Properties

Encapsulation of Lactic Acid Bacteria by Lyophilisation with Its Effects on Viability and Adhesion Properties

Probiotic Supplements: Their Strategies in the Therapeutic and Prophylactic of Human Life-Threatening Diseases

Adjuvant and Beneficial Probiotic Therapy for Women Health

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