Probiotics as potential detoxification tools for mitigation of pesticides: a mini review

Abstract

Pesticides play a key role in agriculture and food production by controlling the insects, weeds, plant pathogens and microbial contaminations. Although they are useful in some aspects, their inappropriate application can induce health problems including carcinogenicity, reproductive toxicity, neurodegenerative diseases and disruption of endocrine system. In this respect, efficient strategies should be applied to reduce pesticide residue in foodstuffs. Several methods have been proposed in food processing for reduction of pesticides residue. Recently, detoxification via microorganisms such as lactic acid bacteria and probiotics has been extensively studied and degradation of pesticides through hydrolytic enzymes has been introduced as the possible mechanism and it has been highlighted that some probiotics harbour pesticide-degrading genes. The aim of this review is to evaluate the efficacy of probiotics in detoxification of pesticides.

Functional Properties and Antimicrobial Activity from Lactic Acid Bacteria as Resources to Improve the Health and Welfare of Honey Bees

“…Many bacteria, including the LABs, appear to have the ability to efficiently remove the HMs through two mechanisms: biosorption and bioaccumulation [ 102 , 103 , 104 , 105 ].…”

Can probiotics win the battle against environmental endocrine disruptors?

“…Probiotics have been found to include pesticide-degrading genes encoded into enzymes with degrading activities such as organophosphorus hydrolases, methyl parathion hydrolases, and organophosphorus acid anhydrases. Gene expression in these microorganisms increased in the presence of pesticides [31]. Studies have shown that pesticides can interact with gut microbiota, affecting the receptor sites of different tissues and organs, destroying the intestinal mucosa and cells that lead to pathological changes [32].…”

Diazinon Reduction In Apple Juice Using Probiotic Bacteria During Fermentation And Refrigerated Storage

“…Population rising and urbanization led to widespread utilization of different kinds of pesticides in agricultural practices during the last century (Mohammadi et al, 2020). However, the occurrence of pesticides residues in different food products is a concern for population health due to their detrimental activity in human body (Cengiz et al, 2006).…”

“…Diazinon (O,O-diethyl-O-[2-isopropyl-6-methyl-4-pyrimidinyl] phosphoro thioate), is one of the most commonly used organophosphorus pesticides for plants' pest control via inhibition of acetyl cholinesterase (Mahmoudpoor Moteshaker et al, 2020;Shah & Iqbal, 2010). It is known as a genotoxic, mutatoxic, cytotoxic and neurotoxic compound which is classi ed as probable human carcinogen (Group 2A) by International Agency for Research on Cancer (IARC) (Mohammadi et al, 2020). Diazinon is generally used in agricultural crops including different types of fruits and vegetables like apples (Vera et al, 2020).…”

“…However, most of these mitigation techniques have some limitations especially high cost of investment and secondary contamination. To this end, bioremediation by microorganisms such as probiotics could be a promising method for pesticide's elimination (Mohammadi et al, 2020). Microbial degradation is a reliable and cost-effective technique with the potential for pesticides' removal from different food products (Islam et al, 2010).…”