Probiotics: wanted dead or alive

Mottet, Christian; Michetti, Pierre

doi:10.1016/j.dld.2004.09.010

Cited by 32 publications

(19 citation statements)

References 33 publications

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“…However, the SPB group had many conspicuous protuberant cells, corresponding with the result that all values of the light microscopic parameters were the highest in the SPB group. This agrees with the observations that probiotic strains could exert beneficial effects in the lower small intestine (Mottet and Michetti, 2005) and that dietary whole yeast or yeast cell wall could improve ileal mucosal development by promoting a greater ileal villus height in broilers (Zhang et al, 2005). A consideration of the higher values of light microscopic parameters in the SPB group than other groups and of the findings of similar studies in the literature, leads to the general conclusion that the present higher values of villi and protuberant cells in the ileum might be hypertrophied by SPB.…”

Section: Discussionsupporting

confidence: 82%

Effect of Sugar Cane Extract, Commercial Probiotic and their Mixture on Growth Performance and Intestinal Histology in Broiler Chickens

Khambualai¹

2010

American Journal of Animal and Veterinary Sciences

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Problem statement:As the intestinal function is intimately affected by fed diets, many kinds of natural substances and probiotics have been supplemented to broilers to raise poultry productivity due to activating intestinal function. Besides, the intestinal histology is clearly altered by intestinal functions. The aim of this study was to investigate whether Sugar Cane Extract (SCE) and commercial probiotic (SPB), either alone or in combination, could improve growth performance and how intestinal histological alterations would be observed in these birds. Approach: A total of 64, 7-dold male broiler chicks were randomly assigned to 4 treatment groups, consisting of 4 replicates of 4 birds each. Commercial mash starter and finisher diets were supplemented with 0.05% SCE, 0.4% SPB, or a mixture of 0.05% SCE and 0.4% SPB (SCE + SPB). Results: Body weight gain was better in all the experimental groups than the control. The greatest improvement was observed in the SCE + SPB group. Most values of villus height, villus area, cell area and cell mitosis in all intestinal segments were higher (p<0.05) in the experimental groups than in the control group. Most epithelial cells on the villus apical surface of the experimental groups were composed of protuberant cells. In addition, cell clusters composed of these cells were observed in the duodenum of the SCE + SPB group and in the jejunum of the SCE group. In the ileum, the SCE + SPB group had the most protuberant cells. Conclusion:The present results of enhanced light microscopic parameters and protuberant epithelial cells in SCE and SPB groups suggest that the intestinal villi and epithelial cells might be hypertrophied by SCE and SPB. The fact that a synergistic effect was observed with regard to growth performance and intestinal histology in the SCE + SPB group suggests that SCE is a good supplement to probiotics.

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Section: Discussionsupporting

confidence: 82%

Effect of Sugar Cane Extract, Commercial Probiotic and their Mixture on Growth Performance and Intestinal Histology in Broiler Chickens

Khambualai¹

2010

American Journal of Animal and Veterinary Sciences

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“…It is well known that probiotics have to transiently colonize to the human gut. Best effect is achieved if the microorganisms colonise the intestinal surface mucus layer since they then can affect the intestinal immune system, displace enteric pathogens, provide antioxidants and antimutagens, and possibly other effects by cell signalling (Vinderola et al, 2004;Mottet and Michetti, 2005).…”

Section: Introductionmentioning

confidence: 99%

“…Probiotics are defined as "living microorganisms, which upon ingestion in certain numbers, exert health benefits beyond inherent basic nutrition" (Mottet and Michetti, 2005). Probiotic microorganisms include many strains of lactic acid bacteria (LAB), and selected strains have activity on intestinal microbiota.…”

Section: Introductionmentioning

confidence: 99%

In vitro characterization of probiotic properties ofPediococcus pentosaceus BH105 isolated from human faeces

et al. 2009

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-In this study, a new bacteriocin-producing strain Pediococcus pentosaceus BH105 was isolated from human faeces and subsequently in vitro probiotic and antagonistic properties were investigated. This strain exhibited high viability at pH 3.0 and in the presence of pepsin, pancreatin and bile salts (0.3%). BH105 was sensitive to 19 of 25 antibiotics and showed no haemolytic activity. The bacteriocin produced by BH105 was active at wide pH range of 2.0 to 11.0 and was heat stable at 80, 90 and 100 °C for 15 min. Bacteriocin activity was inhibited by pepsin, α-chymotrypsin, and proteinase K but not by trypsin, α-amylase, catalase, lysozyme and lipase. The Tricine-SDS-PAGE analysis allowed an approximation of bacteriocin BH105 size about 5 kDa. Pediococcus pentosaceus BH105 was able to adhere to Caco-2 cells (10.12 ± 2.40%) and inhibited the adhesion of Escherichia coli LMG3083 (88.72 ± 5.53%) and Salmonella typhimurium SL1344 (60.64 ± 10.97%).

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“…However, data on potential probiotics will be gradually updated [18,19], thus avoiding further controversies [20]. Moreover, probiotics could be widely indicated in communities such as the sub-Sahara in Africa, where there are high rates of morbidity and mortality due to gastroenteritis in HIV-AIDS patients [21].…”

Section: Discussionmentioning

confidence: 99%

Anti-Inflammatory Effect of Bioflora Probiotic Administered Orally or Subcutaneously with Live or Dead Bacteria

Om¹,

Vasconcelos²,

Catalana³

et al. 2006

Dig Dis Sci

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The anti-inflammatory effect of Bioflora probiotic administered orally or subcutaneously with viable or nonviable bacteria was analyzed in two experimental models of randomly selected female Wistar rats. The use of indomethacin at a dose of 50 mg/kg was associated with gastric necrotic lesions and multiple erosions of the small intestine, with marked mucosal neutrophil infiltrate measured by myeloperoxidase (MPO). Probiotics prevented both gastrointestinal lesions and neutrophil infiltrate (p < 0.001). In the model of carrageenin-induced plantar edema in the rat, the oral or subcutaneous administration of Bioflora with live or dead bacteria proved to prevent plantar edema (p < 0.001). We concluded that Bioflora probiotic given orally or subcutaneously with live or dead bacteria has an anti-inflammatory effect.

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Probiotics: wanted dead or alive

Cited by 32 publications

References 33 publications

Effect of Sugar Cane Extract, Commercial Probiotic and their Mixture on Growth Performance and Intestinal Histology in Broiler Chickens

Effect of Sugar Cane Extract, Commercial Probiotic and their Mixture on Growth Performance and Intestinal Histology in Broiler Chickens

In vitro characterization of probiotic properties ofPediococcus pentosaceus BH105 isolated from human faeces

Anti-Inflammatory Effect of Bioflora Probiotic Administered Orally or Subcutaneously with Live or Dead Bacteria

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