Probiotics with Antimicrobial Activity against Multidrug Resistant Pseudomonas aeruginosa and Acinetobacter baumannii

Lee, Do Kyung; Kim, Min Ji; Kang, Joo Yeon; Park, Jae Eun; Shin, Hea Soon; Ha, Nam Joo

doi:10.7845/kjm.2013.3048

Cited by 4 publications

(6 citation statements)

References 40 publications

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“…Jamalifar et al ( 154 ) reported strong antagonistic activity of Lactobacillus acidophilus fecal isolate against the MDR clinical isolate of Pseudomonas aeruginosa . On similar lines, Bifidobacterium pseudocatenulatum SPM1309 was shown to inhibit MDR P. aeruginosa and A. baumannii ( 155 ). Lactobacillus casei strain exhibited strong activities against MDR Shigella strain ( 156 ).…”

Section: Probiotics Prebiotics and Synbioticsmentioning

confidence: 88%

Antimicrobial Resistance: Its Surveillance, Impact, and Alternative Management Strategies in Dairy Animals

et al. 2018

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Antimicrobial resistance (AMR), one among the most common priority areas identified by both national and international agencies, is mushrooming as a silent pandemic. The advancement in public health care through introduction of antibiotics against infectious agents is now being threatened by global development of multidrug-resistant strains. These strains are product of both continuous evolution and un-checked antimicrobial usage (AMU). Though antibiotic application in livestock has largely contributed toward health and productivity, it has also played significant role in evolution of resistant strains. Although, a significant emphasis has been given to AMR in humans, trends in animals, on other hand, are not much emphasized. Dairy farming involves surplus use of antibiotics as prophylactic and growth promoting agents. This non-therapeutic application of antibiotics, their dosage, and withdrawal period needs to be re-evaluated and rationally defined. A dairy animal also poses a serious risk of transmission of resistant strains to humans and environment. Outlining the scope of the problem is necessary for formulating and monitoring an active response to AMR. Effective and commendably connected surveillance programs at multidisciplinary level can contribute to better understand and minimize the emergence of resistance. Besides, it requires a renewed emphasis on investments into research for finding alternate, safe, cost effective, and innovative strategies, parallel to discovery of new antibiotics. Nevertheless, numerous direct or indirect novel approaches based on host–microbial interaction and molecular mechanisms of pathogens are also being developed and corroborated by researchers to combat the threat of resistance. This review places a concerted effort to club the current outline of AMU and AMR in dairy animals; ongoing global surveillance and monitoring programs; its impact at animal human interface; and strategies for combating resistance with an extensive overview on possible alternates to current day antibiotics that could be implemented in livestock sector.

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Section: Probiotics Prebiotics and Synbioticsmentioning

confidence: 88%

Antimicrobial Resistance: Its Surveillance, Impact, and Alternative Management Strategies in Dairy Animals

et al. 2018

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“…AL-Saadi reported that B. breve had antagonistic activity against methicillin-resistant S. aureus (MRSA) (21). Also, Lee reported that Bifidobacterium strain could have a potential application for alternative therapy in P. aeruginosa and Acinetobacter baumannii (22).…”

Section: Discussionmentioning

confidence: 99%

Antibacterial Effect of Eight Probiotic Strains of Bifidobacterium against Pathogenic Staphylococcus aureus and Pseudomonas aeruginosa

Choi¹,

Shin²

2021

jbv

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Bifidobacterium strains inhibit growth or cell adhesion of pathogenic bacteria and against multidrug-resistant bacteria. Furthermore, when combined with certain antibiotics, probiotics can boost their antibacterial activity. The objective of present report was to evaluate the antibacterial effect of Bifidobacterium spp. In the first part of the investigation, we evaluated the antibacterial activities of viable and inactivated cells, from a total of 12 Bifidobacterium species, on the growth of three different common pathogens associated with multi-drug resistance such as Staphylococcus aureus (S. aureus), Pseudomonas aeruginosa (P. aeruginosa), and Eenterococcus faecalis. Also, eight strains of sonication-inactivated Bifidobacteria exhibited antibacterial activity against S. aureus and P. aeruginosa. Additionally, eight viable Bifidobacterium strains exhibited antibacterial activity on the growth of pathogenic species. Therefore, we observed the antimicrobial activity, of Bifidobacteria against pathogenic bacteria, on the solid medium utilizing the agar well diffusion method. Some Bifidobacterium supernatants such as B. longum and B. pseudocatenulatum, showed synergism with the antibacterial activity of antibiotics. The results exhort that Bifidobacteria could be employed as an effective control for nosocomial pathogenic bacteria, and reduce the risk of the development of S. aureus and P. aeruginosa infection. The present authors propose that Bifidobacteria might be a useful probiotic microorganism, for combining modality with antibiotics, without adverse effects.

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“…Infectious diseases are the second largest cause of fatality in the world recording for more than 13 million deaths annually [4].…”

Section: Introductionmentioning

confidence: 99%

“…Overuse of antibiotics, use of unprescribed antibiotics and continuous use of topical antimicrobial agents has led to the condition where the pathogens become resistant to the used antibiotics [5]. Since the multidrug resistant strains have been increased, the choice of therapy often becomes very limited [4]. The reason for becoming multi-drug resistant in the wound infection is due to the misuse and overuse of antibiotics.…”

Section: Introductionmentioning

confidence: 99%

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Countermeasure for Bacteria Causing Wound Infection

2023

IJBPAS

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The goal of this research was to determine the antibacterial activity of four different medicinal plant extracts including Tridax procumbens, Nigella sativa, Acalypha indica, Vitex negundo as well as the phytochemicals present in the extract. In this study, ethanol and methanol solvents were used for the plant extraction. The antibacterial activity of crude extracts of four plants was investigated using agar well diffusion method against Staphylococcus aureus, Enterococci sp. Pseudomonas aeruginosa, Escherichia coli, Klebsiella sp., and Proteus sp. by agar well diffusion method. Standard antibiotic Ciprofloxacin is used as a positive control. The best plant extract was analyzed qualitatively for the presence of phytochemicals. Both the methanolic and ethanolic extract of Nigella sativa seeds showed higher zone of inhibition against gram-positive bacteria viz.Staphylococcus aureus, Enterococci when compared to gram-negative organisms. Among the four plant extracts, N. sativa seeds extract showed effective inhibition against the tested organisms. Phytochemical analysis revealed that tannin, saponin, alkaloids, flavonoids, phenol were present in the methanolic extract of N. sativa but terpenoids was absent. N.

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Probiotics with Antimicrobial Activity against Multidrug Resistant Pseudomonas aeruginosa and Acinetobacter baumannii

Cited by 4 publications

References 40 publications

Antimicrobial Resistance: Its Surveillance, Impact, and Alternative Management Strategies in Dairy Animals

Antimicrobial Resistance: Its Surveillance, Impact, and Alternative Management Strategies in Dairy Animals

Antibacterial Effect of Eight Probiotic Strains of Bifidobacterium against Pathogenic Staphylococcus aureus and Pseudomonas aeruginosa

Countermeasure for Bacteria Causing Wound Infection

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