Problems of Chronic Pyelonephritis

Prolonged Maintenance Chemotherapy in the Management of Urinary Infection in Childhood

“…These children might be expected to do least well. Any underlying abnormality predisposes to recurrences, and patients with these repeated infections would be liable to chronic pyelonephritic scarring (Kleeman et al, 1960;Rosenheim, 1963). Moreover, experimental evidence suggests that such scarring would be likely to facilitate further renal infection (De Navasquez, 1956;Beeson et al, 1957).…”

Management of Unilateral Chronic Pyelonephritis

“…Spontaneous resolution occurs in the majority of cases of childhood reflux, so the operation may be unnecessary. Nevertheless, Gower (1976) and our group (Arze et al 1982) found persisting reflux in about one-third of adults with chronic pyelonephritis and it may be more frequent than this in those who develop hypertension (Rosenheim 1963). However, even if it does persist, there is at present little evidence that surgical correction of reflux is superior to medical measures to control infection.…”

Oral Contraceptives and Liver Damage

“…The same principle has gained favour in the treatment of patients with recurrent and chronic urinary infections when there is no obstructive lesion amenable to surgery (Stansfeld and Webb, 1954 ;Rosenheim, 1963). In patients with recurrent or chronic biliary infection any obstructive lesion should, if possible, be relieved surgically.…”