Problemy hematologiczne w okresie ciąży

Kopeć, Izabella

doi:10.5603/hem.2016.0028

Cited by 1 publication

(1 citation statement)

References 37 publications

(72 reference statements)

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“…Additionally, it may result in a slightly decreased vitamin B 12 concentration (in about 10-28% of women) [45] and a slight decrease in platelet count [46]. It is also worth noting in that during this time (i.e., 17-36 weeks) the number of white blood cells increases by about 20% due to increased hormonal activity (e.g., glucocorticosteroids) and cytokine synthesis (an increase in granulocyte-macrophage colony-stimulating factor) [47]. The World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) define anemia in the 1st and 3rd trimesters as Hgb concentrations below 11.0 g/dL and hematocrit below 33%.…”

Section: Iron (Fe)mentioning

confidence: 99%

The Role of Fe, Zn, and Cu in Pregnancy

2020

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Iron (Fe), copper (Cu), and zinc (Zn) are microelements essential for the proper functioning of living organisms. These elements participatein many processes, including cellular metabolism and antioxidant and anti-inflammatory defenses, and also influence enzyme activity, regulate gene expression, and take part in protein synthesis. Fe, Cu, and Zn have a significant impact on the health of pregnant women and in the development of the fetus, as well as on the health of the newborn. A proper concentration of these elements in the body of women during pregnancy reduces the risk of complications such as anemia, induced hypertension, low birth weight, preeclampsia, and postnatal complications. The interactions between Fe, Cu, and Zn influence their availability due to their similar physicochemical properties. This most often occurs during intestinal absorption, where metal ions compete for binding sites with transport compounds. Additionally, the relationships between these ions have a great influence on the course of reactions in the tissues, as well as on their excretion, which can be stimulated or delayed. This review aims to summarize reports on the influence of Fe, Cu, and Zn on the course of single and multiple pregnancies, and to discuss the interdependencies and mechanisms occurring between Fe, Cu, and Zn.

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Section: Iron (Fe)mentioning

confidence: 99%