Processo de cura das feridas: cicatrização fisiológica

Isaac, César; Ladeira, Pedro Ribeiro Soares de; Rego, F.; Aldunate, Johnny Conduta Borda; Ferreira, Marcus Castro

doi:10.11606/issn.1679-9836.v89i3/4p125-131

Cited by 62 publications

(89 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These cells align and attach themselves to the thicker collagen fibers, pulling them together and thus greatly contributing to the healing process 18,19 . The number of fibroblasts confirms study data, indicating that electrical stimulation improves lesion regeneration, since it promotes cell migration, stimulates fibroblasts and increases protein synthesis 17,20 . Isolated application of topical insulin showed no significant difference in all analyzed variables, though insulin is known to stimulate growth and the development of different types of cells 21 .…”

Section: Resultssupporting

confidence: 77%

Efeito da estimulação elétrica de alta voltagem e insulina tópica em lesão cutânea experimental

et al. 2016

View full text Add to dashboard Cite

| This study aims to evaluate the effect of cathodic high voltage electrical stimulation (HVES), associated with topical insulin, on rat integumentary lesions.For this purpose, 42 Wistar rats (240±30 g) were submitted to surgical removal of 1 cm 2 of dorsal skin and divided into six groups (n=7), treated for seven consecutive days: Control (C), placebo electrical stimulation (PES), cathodic electrical stimulation (ES), topical insulin (TI), placebo insulin (PI) and HVES associated with topical insulin (ES+I).HVES was administered 24 hours after surgery, 30 minutes per day, with a frequency of 100 Hz and a mean voltage of 60 V, maintained at the motor threshold. Lesion areas were

show abstract

Section: Resultssupporting

confidence: 77%

Efeito da estimulação elétrica de alta voltagem e insulina tópica em lesão cutânea experimental

et al. 2016

View full text Add to dashboard Cite

show abstract

“…During this initial stage of repair, the type III collagen is predominant, synthesized by fibroblasts in the granulation tissue. 30 …”

Section: Proliferative Stagementioning

confidence: 99%

Wound healing - A literature review

Gonzalez

Costa²,

Andrade

et al. 2016

An. Bras. Dermatol.

1,225

822

View full text Add to dashboard Cite

Regeneration and tissue repair processes consist of a sequence of molecular and cellular events which occur after the onset of a tissue lesion in order to restore the damaged tissue. The exsudative, proliferative, and extracellular matrix remodeling phases are sequential events that occur through the integration of dynamic processes involving soluble mediators, blood cells, and parenchymal cells. Exsudative phenomena that take place after injury contribute to the development of tissue edema. The proliferative stage seeks to reduce the area of tissue injury by contracting myofibroblasts and fibroplasia. At this stage, angiogenesis and reepithelialization processes can still be observed. Endothelial cells are able to differentiate into mesenchymal components, and this difference appears to be finely orchestrated by a set of signaling proteins that have been studied in the literature. This pathway is known as Hedgehog. The purpose of this review is to describe the various cellular and molecular aspects involved in the skin healing process.

show abstract

“…It can be divided into three phases: 1 st or exudative inflammation; 2 nd or proliferative/ fibroblastic (granulation tissue with deposition of extracellular matrix); 3 rd or remodeling/maturation [1][2][3][4][5][6] . The knowledge of each of these stages is important to guide appropriate adjuvant therapy to improve biological reaction 6 .…”

Section: Introductionmentioning

confidence: 99%

Schinus terebinthifolius raddi (Aroeira) and Orbignya phalerata mart. (Babassu) effect in cecorrahphy healing in rats

et al. 2016

View full text Add to dashboard Cite

METHODS:Fifty four rats were used, distributed into three groups randomly: aroeira, babassu and control, which were divided into three subgroups (six animals) according to the time of the deaths (7, 14, 21 days). All underwent the same surgical procedure, cecotomy and cecorrhaphy. The animals in group aroeira and babassu received daily dose of 100 mg/kg of hydroalcoholic extract and 50 mg/kg of aquous extract respectively, by gavage. The control group received only saline solution. The parameters evaluated were: macroscopic changes, ,resistance test to air insufflations and histological changes. RESULTS:All animals showed good healing without infection. All groups presented adhesions between cecum and neighboring organs.The resistance test insufflating of atmospheric air showed progressive increase of pressure according to the days in the aroeira group, and decrease in babassu group, without significant difference. Microscopy showed significant difference in the polymorphonuclear, hyperemia, angiogenesis, fibroblast proliferation and collagen histological variables in the 14 th day. CONCLUSION:Hydroalcoholic extract of aroeira and the aqueous extract of babassu favored the healing process in cecorrhaphy in rats.

show abstract

Processo de cura das feridas: cicatrização fisiológica

Cited by 62 publications

References 8 publications

Efeito da estimulação elétrica de alta voltagem e insulina tópica em lesão cutânea experimental

Efeito da estimulação elétrica de alta voltagem e insulina tópica em lesão cutânea experimental

Wound healing - A literature review

Schinus terebinthifolius raddi (Aroeira) and Orbignya phalerata mart. (Babassu) effect in cecorrahphy healing in rats

Contact Info

Product

Resources

About