“…2–6 As Rosen and Percec predicted in 2007, 2 a this technique has now become a major focus for chemists, as evidenced by a large number of original research publications and reviews. 3,6 a , b , e , f ,7 In most fields of chemical research including materials science, 2 c ,6 a ,8 organic synthesis, 3,6 b , c , e , f ,7,9 extraction and separation of natural products, 10 pharmacy, 11 carbohydrate chemistry 12 and biomass valorization, 13 the mechanochemical technique has been proved effective and reliable. The following are the frequently noted advantages of mechanochemical organic synthesis:…”