Profil Kreatinin dan Nitrogen Urea Darah pada Anak Sapi Friesian Holstein yang Disuplementasi Zn

Abstract

Parameter kreatinin dan nitrogen urea darah atau blood urea nitrogen (BUN) dapat digunakan sebagai indikator untuk melihat adanya gangguan fungsi ginjal. Penelitian ini bertujuan untuk mengetahui kadar kreatinin dan BUN dalam serum anak sapi Friesian Holstein (FH) yang diberi suplementasi mineral Zn di dalam pakan. Penelitian ini menggunakan 9 ekor anak sapi FH yang sehat secara klinis dan umur berkisar antara 6-10 bulan. Hewan dibagi menjadi 3 kelompok, yaitu kelompok tanpa suplementasi Zn, kelompok yang diberi suplementasi Zn sebesar 60 ppm, dan kelompok yang diberi suplementasi Zn sebesar 120 ppm. Pengambilan sampel darah dilakukan melalui vena jugularis sebelum pemberian Zn dan setiap bulan setelah pemberian Zn selama 3 bulan. Sampel darah dalam bentuk serum dianalisis untuk kadar kreatinin dan BUN menggunakan alat spektrofotometer. Hasil pemeriksaan memperlihatkan bahwa kadar kreatinin darah berkisar antara 0,64 sampai 0,77 mg/dL, dan kadar BUN berkisar antara 8 sampai 19 mg/dL. Kadar kreatinin dan BUN darah pada anak sapi FH masih berada pada kisaran normal. Oleh karena itu suplementasi Zn 60 ppm maupun 120 ppm yang diberikan selama tiga bulan pada anak sapi FH relatif aman dan tidak menggangu fungsi ginjal.Kata kunci: mineral Zn, BUN, kreatinin, anak sapi Friesian Holstein. (Creatinin and Blood Urea Nitrogen Profiles on Friesian Holstein Calves Supplemented by Zn)Creatinine and blood urea nitrogen (BUN) can be used for indicator renal disfuction. The objective of this experiment was to study the concentration of creatinine and blood urea nitrogen in Friesian Holstein (FH) calves, received feed supplemented by Zn. Nine healthy Holstein calves, 6-10 months old were used in this experiment. The calves were devided into 3 groups, consisted of three calves, i.e. no supplementation (control), 60 ppm and 120 ppm of Zn supplementation. Blood sample were collected from jugular vein, before dan after supllementation Zn every month untill 3 months. Blood urea nitrogen and creatinine concentrations in serum were analysed using spectrophotometer. Results of the experiment had indicated that the creatinine and BUN concentration ranging between 0,64-0,77 mg/dL and 8-19 mg/dL, respectively. In conclusion, concentration of creatinine and Blood urea nitrogen were in a normal range. So the supplementation of Zn 60 and 120 ppm were given for three months in Friesian Holstein calves relatively safe for renal function.Keywords: zinc, blood urea nitrogen, creatinine, Friesian Holstein calves.

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