Profile and Antimicrobial Resistance Patterns of Bacteria isolated from Patients with Respiratory Tract Infections in Ile-Ife Metropolis

Erythromycin Resistance in Bacterial Isolates from Patients with Respiratory Tract Infections in Ikere-Ekiti, Nigeria

“…This is similar to the study by Motayo et al (2012) that reported the highest occurrence in the age range of 31-45 years. Previous studies had reported the highest occurrence among the age group 20-29 years (Taura et al, 2013) and 21-30 years (Osevwe et al, 2017) which is in contrast to this study. The occurrence of respiratory diseases/symptoms of patients recruited in the study showed that lower respiratory tract infections (LRIs) 117 (58.5%) were the most common followed by cough 41 (20.5%) and difficulty in breathing 24 (12%).…”

“…exhibited resistance to erythromycin which is a manifestation of a possible acquisition of erythromycin resistance genes by this organism. Also, Osevwe et al (2017) had also reported resistance of Streptococcus pneumoniae to gentamicin (100%), cloxacillin (71.4%), and chloramphenicol (85.7%) which is in agreement with this study E. coli was 90% sensitive to gentamicin, trimethoprim-sulfamethoxazole, and 100% resistant to amoxicillin-clavulanic acid, and tetracycline. In a similar study, Taura et al (2013) reported that E. coli was sensitive to gentamicin, Motayo et al (2012) also reported 25% of E. coli isolates were sensitive to gentamicin.…”

“…The prevalence of Klebsiella spp. (25%) in this study had been previously reported as the most common bacteria isolated from RTIs in other studies (Egbe et al, 2011;Osevwe et al, 2017). Haemophillus influenzae was reported by Nweze et al (2012) as the most frequently isolated pathogen from the respiratory tract of children in southeastern Nigeria which is in contrast to this study.…”

“…This study screened a total of 200 patients having respiratory infections 124 (62%) were males and 76 (38%) were females. In a similar study, Osevwe et al (2017) also reported higher male patients (62.2%) than female patients (38.8%). The finding attributed the involvement of males in different activities like consumption of alcohol and smoking which may aggravate the risk of acquiring RTIs (Grau et al, 2014).…”

“…The burden of respiratory diseases is not well studied particularly in developing countries where treatment of respiratory tract infection is based on empirical therapy, probably due to increased cost of laboratory services and high levels of poverty. Also, ignorance and distribution of fake drugs have likewise contributed to antimicrobial resistance (El-Astal, 2004;Osevwe et al, 2017).…”