2024
DOI: 10.1186/s43556-024-00237-4
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Profiling immune cell-related gene features and immunoregulatory ceRNA in ischemic stroke

Yanbo Li,
Sicheng Liu,
Linda Wen
et al.

Abstract: Molecules in immune cells plays a vital role in the pathogenesis of ischemic stroke (IS). The aim of this study is to profile the landscape of molecules on the basis of immune cells in IS peripheral blood and construct an immunoregulatory competing endogenous RNA (ceRNA) network. We collected and combined multiple public transcriptome datasets from the peripheral blood of IS patients and healthy controls. CIBERSORT deconvolution revealed that the proportions of CD8 and CD4 naive T cells, monocytes, and neutrop… Show more

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