Profiling of phenolic and other compounds from Egyptian cultivars of chickpea (Cicer arietinum L.) and antioxidant activity: a comparative study

Mekky, Reham Hassan; Contreras, María del Mar; El-Gindi, Mohamed Roshdi; Abdel-Monem, Azza R.; Abdel‐Sattar, Essam; Segura‐Carretero, Antonio

doi:10.1039/c4ra13155j

Cited by 90 publications

(83 citation statements)

References 72 publications

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“…This compound was previously identified in P. avium stems as reported by Bastos et al Furthermore, two isomers of naringenin were detected (peaks 28 and 29) showing the same [M – H] − at m/z 271.0612. The main MS/MS ions were m/z 119.0501 and 151.0036, in agreement with data previously reported by Mekky et al Peak 32, detected at 16.14 min and with m/z 253.0506, was tentatively assigned as chrysin according to the molecular formula provided for its accurate mass, fragmentation pattern and literature data . Methylnaringenin (peak 33) was tentatively identified in P. avium stems.…”

Section: Resultssupporting

confidence: 88%

New technological approaches for recovering bioactive food constituents from sweet cherry (Prunus avium L.) stems

Nastić

Lozano-Sánchez²,

Borrás-Linares³

et al. 2019

Phytochemical Analysis

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Introduction In recent years, an increasing interest in biological properties of sweet cherry (Prunus avium L.) stems has resulted in increased attention for advanced extraction techniques and their optimisation. Objectives In the present study chemical profiles of P. avium stems extracts obtained by selected emerging technologies, such as pressurised liquid extraction (PLE) and supercritical fluid extraction (SFE), under different experimental conditions were compared. Material and Methods All SFEs were carried out at 40°C in a dynamic mode with different solvent combinations (CO2 plus ethanol at 7 and 15%) and pressures (150 and 300 bar). The PLE experiments were performed in a static mode for all tested combinations of extraction solvent (ethanol–water from 0% to 100%) at temperatures ranging from 40 to 200°C. A complete analytical characterisation of cherry stem extracts was performed by high‐performance liquid chromatography coupled to electrospray ionisation quadrupole time‐of‐flight mass spectrometry (HPLC‐ESI‐QTOF‐MS). Results PLE showed to be more efficient than SFE removing a wide variety of compounds with different polarities being phenols the most abundant, whereas SFE resulted in a higher amount of fatty acids and derivatives. Chemical characterisation of the extracts was carried out by HPLC‐ESI‐QTOF‐MS yielding in total 42 identified compounds, among which 22 compounds were identified in P. avium stems for the first time. Conclusion These results point out the possibility of sweet cherry stem extracts to be incorporated in formulations manufactured by food and pharmaceutical industry. Also, these new thermal and high‐pressure industrial technologies proved to be promising candidates in the valorisation of sweet cherry by‐product.

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Section: Resultssupporting

confidence: 88%

New technological approaches for recovering bioactive food constituents from sweet cherry (Prunus avium L.) stems

Nastić

Lozano-Sánchez²,

Borrás-Linares³

et al. 2019

Phytochemical Analysis

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“…The first compounds that appeared were sugars and organic acids and last ones were secoiridoids and lignans (Table ). Furthermore, UV–vis detection data were used to primarily characterise the chemical structures, which showed equivalent to results in accordance with previous studies (Talhaoui et al, ; Klen et al, ; Mekky et al, ; Salido et al, ; Ammar et al, , ). Mass accurate determinations in the negative ionisation mode helped to identify the molecular formula of each molecular ion.…”

Section: Resultssupporting

confidence: 84%

RP‐HPLC‐DAD‐ESI‐QTOF‐MS based metabolic profiling of the potential Olea europaea by‐product “wood” and its comparison with leaf counterpart

Ammar

Contreras

Gargouri

et al. 2017

Phytochemical Analysis

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“…Based on the MS and MS/MS data, the peaks 1 – 11 were identified as vanillic acid‐4‐ O ‐glucopyranoside, 2,5‐di‐hydroxybenzoic acid glucopyranoside, sinapic acid glucopyranoside, 1‐caffeoylquinic acid, kaempferol‐3,4′‐ O ‐di‐glucopyranoside, quercetin‐3,7‐ O ‐di‐glucopyranoside, naringenin‐3‐ O ‐glucopyranosyl‐rhamnoside, daidzein, biochanin A‐7‐ O ‐glucopyranoside, pratensein, and biochanin A, respectively. The data shown in Table are consistent with findings of previous studies .…”

Section: Resultssupporting

confidence: 92%

“…Cicer arietinum (chickpea) is part of the basic diet in many countries, with several cultivars distributed across the world. Scientific interest in the seeds of C. arietinum has arisen primarily because of the presence of phenolic and flavonoid compounds in them , which have been shown to possess health benefits. Several studies have reported that the extract of C. arietinum has anticancer activity, especially against breast cancer .…”

Section: Introductionmentioning

confidence: 99%

In vitro screening and isolation of human aromatase inhibitors from Cicer arietinum by a novel continuous online method combining chromatographic techniques

Zhang

Liu

et al. 2017

J of Separation Science

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Ultrafiltration liquid chromatography with mass spectrometry can efficiently and rapidly screen and identify ligands from the seeds of Cicer arietinum for human aromatase. Using this method, we identified 11 major compounds, including organic acids, organic acid glycosides, flavone glycosides, isoflavones, and isoflavone glycosides, as potent human aromatase inhibitors. A continuous online method, including pressurized liquid extraction, countercurrent chromatography, and preparative liquid chromatography, was developed for scaling up the production of these compounds with high purity and efficiency. The bioactivity of the separated compounds was assessed by an in vitro enzyme inhibition assay. This novel approach using a combination of ultrafiltration liquid chromatography with mass spectrometry and pressurized liquid extraction with countercurrent chromatography and preparative liquid chromatography as well as an in vitro enzyme inhibition assay could be applied to efficiently screen and isolate human aromatase inhibitors from complex samples and to the large-scale production of functional food and nutraceutical ingredients.

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Profiling of phenolic and other compounds from Egyptian cultivars of chickpea (Cicer arietinum L.) and antioxidant activity: a comparative study

Abstract: The metabolic profiling of seven Egyptian cultivars of chickpeaviaRP-HPLC-DAD-ESI-QTOF-MS enabled the characterization of 96 phenolic compounds.

Cited by 90 publications

References 72 publications

New technological approaches for recovering bioactive food constituents from sweet cherry (Prunus avium L.) stems

New technological approaches for recovering bioactive food constituents from sweet cherry (Prunus avium L.) stems

RP‐HPLC‐DAD‐ESI‐QTOF‐MS based metabolic profiling of the potential Olea europaea by‐product “wood” and its comparison with leaf counterpart

In vitro screening and isolation of human aromatase inhibitors from Cicer arietinum by a novel continuous online method combining chromatographic techniques

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