Prognostic Impact and Post-operative Evaluation of Volumetric Measurement of the Cerebellopontine Cistern in Trigeminal Neuralgia Using 3 Tesla Magnetic Resonance Imaging

Obata, Yoshiki; Kawano, Yoshihisa; Tanaka, Yoji; Maehara, Taketoshi

doi:10.2176/nmc.oa.2017-0157

Cited by 6 publications

(6 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…MR could predict prognosis of primary TN. Obata et alfound that smaller preoperative cistern deviation index was positively correlated to the recurrence of TN after microvascular decompression (MVD) [ 14 ]. What’s more, Andrei Brînzeu et al [ 28 ] and Patrick W Hitchon et al [ 30 ] found degree of NVC on MR could accurately predict the outcomes of patients with TN who underwent MVD.…”

Section: Discussionmentioning

confidence: 99%

Correlation study between multiplanar reconstruction trigeminal nerve angulation and trigeminal neuralgia

Sun

Huang

et al. 2022

BMC Neurol

View full text Add to dashboard Cite

Objectives Neurovascular compression (NVC) produces morphological changes on the trigeminal nerve root is considered the cause of trigeminal neuralgia (TN), but there were some patients with TN found no NVC, and also NVC was found in asymptomatic individuals. Many studies found tight relationships of TN and morphological structures of trigeminal nerve. We designed this study to explore the correlation between multiplanar reconstruction (MPR) trigeminal nerve angulation (TNA) and TN. Methods Patients with classical symptoms of TN were recruited as observation group (OG) in this study, 50 healthy controls were enrolled as control group (CG), the OG was further subtyped into young patients (YP), middle-aged patients (MP) and old patients (OP) based to the onset age of symptoms, and also divided into patients with or without trigger maneuvers (TM) based on the presence of TM or not. All the participants underwent magnetic resonance (MR) examinations in same device, bilateral TNA measurements were carried out in OG and CG, then TNA was compared between different groups or subgroups. All images were interpreted by two radiologists who were blinded to the study, diagnosis of TN was made by two senior neurosurgery professors. Result Ultimately, 95 patients with primary TN were recruited in OG, aged from 25 to 84 (61.15 ± 12.70) years with a course of 0.5 to 30 (5.03 ± 5.41) years, their onset age ranged from 24 to 82 (56.13 ± 11.98) years. There were 34 males and 61 females in OG, and 58 cases involved right side. The CG aged from 22 to 85 (61.86 ± 13.03) years. No statistical difference was found between the age of OG and CG(p = 0.76), and also the bilateral TNA of CG (154.92 ± 16.90° vs 155.55 ± 17.03°, p > 0.05), while TNA of OG was significantly smaller than CG (150.78 ± 11.29° vs 155.24 ± 16.88°, p = 0.019). In OG, TNA on the affected side was significantly smaller than the unaffected side (149.29 ± 12.44° vs 152.27 ± 9.85°, p = 0.014). TNA showed a positive correlation with onset age of patients with TN, as TNA on the affected side of YP was significantly smaller than MP and OP (139.00 ± 11.64° vs 148.86 ± 11.54°, 139.00 ± 11.64° vs 152.18 ± 12.61°, p = 0.004 and 0.026). Furthermore, patients with TM showed smaller TNA than those without TM (147.05 ± 11.30° vs 164.75 ± 8.39°, p < 0.001). Conclusions This study suggested that TNA might play a role in TN, small TNA could be a risk factor of TN. Furthermore, patients with small TNA are more likely to combine with TM, but more studies are needed to explore the exact role of TNA in TN.

show abstract

Section: Discussionmentioning

confidence: 99%

Correlation study between multiplanar reconstruction trigeminal nerve angulation and trigeminal neuralgia

Sun

Huang

et al. 2022

BMC Neurol

View full text Add to dashboard Cite

show abstract

“…The reformatted images were magnified to facilitate the measurement of the length and volume of the target. Morphometric length and volume parameters were determined and measured as previously described [ 15 , 22 , 23 ]. The length measurements were calculated by manually drawing on axial images with a section thickness of 0.5 mm, and the volume measurements were calculated automatically with the 3D reconstruction software.…”

Section: Methodsmentioning

confidence: 99%

Morphometric examination of trigeminal nerve and its adjacent structures in patients with trigeminal neuralgia: a case-control study

Kundakci¹,

Doğan²,

Kara³

et al. 2022

Turkish Journal of Medical Sciences

View full text Add to dashboard Cite

Background/aim Morphological differences that can lead the trigeminal nerve to neurovascular conflict and a new solitary pontine lesion are associated with the pathogenesis of trigeminal neuralgia (TN). In this case-control study, we aimed to contribute to the current discussions about the pathogenesis of TN by investigating the anatomical structures that may have an effect on the morphometric parameters of the trigeminal nerve. Materials and methods This study included 25 patients with TN followed up for pain in the Department of Algology, Faculty of Medicine, and 25 age- and gender-matched controls. We performed morphometric measurements including the length and volume of the trigeminal nerve, cerebellopontine cistern, pons, and posterior fossa in the MRIs of these individuals. Comparative analyses were performed for the mean of the affected and unaffected sides of the TN patients and the right, left, and both sides of the control group. Results In patients with TN, on the affected side, length and volume of the trigeminal nerve and cerebellopontine cistern volume were found smaller than controls (p < 0.05). Pons volume was higher in patients with TN compared to controls (p < 0.05). The length of the affected nerve was significantly related to prepontine cistern length and cerebellopontine cistern volume (p < 0.05). Conclusion The cerebellopontine cistern volume has a significant impact on the morphometric characteristics of the trigeminal nerve. Especially, whether the increase in the volume of pons causes a decrease in the volume of cerebellopontine cistern should be clarified with further research.

show abstract

“…Hung et al suggested that diffusion tensor imaging (DTI) could assist the diagnosis of TN 16 . Researches revealed positive correlations between nerve atrophy, small trigeminal pontine angle, small CPA cistern cross-sectional area, short trigeminal nerve, thin trigeminal nerve and TN 6,11,12,19,29,30,40 .Wei et al reported that three-dimensional time-of-ight (3D-TOF) MR angiography imaging showed a sensitivity rate (SR) of 74.0% in the evaluation of NVC, the SR could reach to 88.4% as it was accompanied by 3D-CISS 38 . Boecher et al reported an 88.9% of positive rate (PR) and 88.5% of SR of NVC from high-de nition MR angiography 3 .…”

Section: Value Of Mr In Diagnosis Of Primary Tnmentioning

confidence: 99%

“…(Table 6) Many factors in uence the outcome of TN after MVD, MR might predict prognosis of primary TN as well. Obata et al found that smaller preoperative cistern deviation index was positively correlated to the recurrence of TN after MVD 29 . What's more, Brinzeu et al 4 and Hitchon et al 13 found that the degree of NVC on MR could accurately predict the outcomes of TN after MVD.…”

Section: Value Of Mr In Diagnosis Of Primary Tnmentioning

confidence: 99%

See 1 more Smart Citation

Correlation study between multiplanar reconstruction trigeminal nerve angulation and trigeminal neuralgia

Sun

Huang

Li³

et al. 2022

Preprint

View full text Add to dashboard Cite

Objectives Despite neurovascular compression (NVC) is now widely accepted mechanism of trigeminal neuralgia (TN), there were some patients found no NVC, and also NVC was found in asymptomatic individuals. Here, we aimed to explore the correlation between multiplanar reconstruction (MPR) trigeminal nerve angulation (TNA) and TN. Methods From May 2020 to November 2021, 50 healthy controls were enrolled as control group (CG), 95 patients with primary TN were enrolled as observation group (OG), which was further subtyped into young patients (YP), middle-aged patients (MP) and old patients (OP) according to onset age of TN symptoms. Patients was also divided into patients with or without evoked actions according to the presence of evoked actions or not. Bilateral TNA measurements were carried out in OG and CG, image parameters were compared between different groups or subgroups. All images were interpreted by two radiologists who were blinded to the study. Result No statistical difference of bilateral TNA of CG was found, TNA of OG was significantly smaller than CG. In OG, TNA on the affected side was significantly smaller than the unaffected side. TNA showed a positive correlation with age, as TNA on the affected side of YP was significantly smaller than MP and OP. Patients with evoked actions showed smaller TNA than patients without evoked actions. Conclusions This study suggested that TNA might play a role in TN, small TNA could be a risk factor of TN. Furthermore, patients with small TNA are more likely to combine with evoked actions., but more studies are needed to explore the exact role of TNA in TN.

show abstract

Prognostic Impact and Post-operative Evaluation of Volumetric Measurement of the Cerebellopontine Cistern in Trigeminal Neuralgia Using 3 Tesla Magnetic Resonance Imaging

Cited by 6 publications

References 31 publications

Correlation study between multiplanar reconstruction trigeminal nerve angulation and trigeminal neuralgia

Correlation study between multiplanar reconstruction trigeminal nerve angulation and trigeminal neuralgia

Morphometric examination of trigeminal nerve and its adjacent structures in patients with trigeminal neuralgia: a case-control study

Correlation study between multiplanar reconstruction trigeminal nerve angulation and trigeminal neuralgia

Contact Info

Product

Resources

About