“…Although an Internet-based survey of MDS patients' QOL has been published, 10 no MDS-specific QOL measure has been widely adopted for clinical or research use. Researchers aiming to assess the impact of MDS and its treatments 9,[11][12][13][14][15][16][17][18] on QOL have most often used generic measures such as the Short-Form Health Survey (SF-36), 19 or cancer-specific scales such as the European Organization for Research and Treatment of Cancer's QLQ-C30 20 and the Functional Assessment of Cancer Therapy-Anemia (FACT-An). 21 While these measures are useful, they are not specific enough to contain all of the elements important to MDS-related QOL, and may contain several less relevant items.…”